Technology Process of 3-(3,5-dimethoxyphenyl)4-methylpent-4-enoic acid
There total 4 articles about 3-(3,5-dimethoxyphenyl)4-methylpent-4-enoic acid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: diisobutylaluminium hydride / dichloromethane / -78 °C / Inert atmosphere
2: propionic acid / toluene / 12 h / 150 °C / Inert atmosphere
3: water; lithium hydroxide / tetrahydrofuran; methanol / Inert atmosphere
With
water; diisobutylaluminium hydride; propionic acid; lithium hydroxide;
In
tetrahydrofuran; methanol; dichloromethane; toluene;
2: Johnson-Claisen rearrangement;
DOI:10.1021/ol202881q
- Guidance literature:
-
Multi-step reaction with 2 steps
1: propionic acid / toluene / 12 h / 150 °C / Inert atmosphere
2: water; lithium hydroxide / tetrahydrofuran; methanol / Inert atmosphere
With
water; propionic acid; lithium hydroxide;
In
tetrahydrofuran; methanol; toluene;
1: Johnson-Claisen rearrangement;
DOI:10.1021/ol202881q
- Guidance literature:
-
With
water; lithium hydroxide;
In
tetrahydrofuran; methanol;
Inert atmosphere;
DOI:10.1021/ol202881q
