2-acetamido-4-(1,2,4-triazolyl)-6-(3,4-dimethoxyphenyl)pyrido[3,2-d]pyrimidine

Base Information

Chemical Name:2-acetamido-4-(1,2,4-triazolyl)-6-(3,4-dimethoxyphenyl)pyrido[3,2-d]pyrimidine
CAS No.:897359-77-2
Molecular Formula:C₁₉H₁₇N₇O₃
Molecular Weight:391.389
Hs Code.:

Synonyms:2-acetamido-4-(1,2,4-triazolyl)-6-(3,4-dimethoxyphenyl)pyrido[3,2-d]pyrimidine

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Chemical Property of 2-acetamido-4-(1,2,4-triazolyl)-6-(3,4-dimethoxyphenyl)pyrido[3,2-d]pyrimidine

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Technology Process of 2-acetamido-4-(1,2,4-triazolyl)-6-(3,4-dimethoxyphenyl)pyrido[3,2-d]pyrimidine

There total 1 articles about 2-acetamido-4-(1,2,4-triazolyl)-6-(3,4-dimethoxyphenyl)pyrido[3,2-d]pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 288-88-0
1,2,4-Triazole

: 897359-76-1
2-acetamido-6-(3,4-dimethoxyphenyl)pyrido[3,2-d]pyrimidin-4(3H)-one

: 897359-77-2
2-acetamido-4-(1,2,4-triazolyl)-6-(3,4-dimethoxyphenyl)pyrido[3,2-d]pyrimidine

Guidance literature:: With triethylamine; trichlorophosphate; In acetonitrile; at 20 ℃; for 72h;

Reference yield: 79.0%

: 110-85-0
piperazine

: 897359-77-2
2-acetamido-4-(1,2,4-triazolyl)-6-(3,4-dimethoxyphenyl)pyrido[3,2-d]pyrimidine

: 897360-08-6
2-acetamido-4-(N-piperazinyl)-6-(3,4-dimethoxyphenyl)pyrido[3,2-d]pyrimidine

Guidance literature:: In 1,4-dioxane; at 20 ℃; for 16 - 24h; Product distribution / selectivity; Heating / reflux;

Reference yield: 60.0%

: 883554-87-8
piperidine-3-carboxylic acid isobutyl amide

: 897359-77-2
2-acetamido-4-(1,2,4-triazolyl)-6-(3,4-dimethoxyphenyl)pyrido[3,2-d]pyrimidine

: 897362-03-7
2-amino-4-[(3-carboxylic acid isobutylamide)piperidin-1-yl]-6-(3,4-dimethoxyphenyl)pyrido[3,2-d]pyrimidine

Guidance literature:: piperidine-3-carboxylic acid isobutyl amide; 2-acetamido-4-(1,2,4-triazolyl)-6-(3,4-dimethoxyphenyl)pyrido[3,2-d]pyrimidine; With N-ethyl-N,N-diisopropylamine; In 1,4-dioxane; for 2h; Heating / reflux;

With water; potassium carbonate; In methanol; for 2h; Heating / reflux;