2,4-Dichloro-6-(4-fluorophenyl)pyrimidine

Base Information

Chemical Name:2,4-Dichloro-6-(4-fluorophenyl)pyrimidine
CAS No.:833472-84-7
Molecular Formula:C10H5 Cl2 F N2
Molecular Weight:243.068
Hs Code.:2933599090
DSSTox Substance ID:DTXSID30469828
Nikkaji Number:J2.282.940H
Wikidata:Q82297713
Mol file:833472-84-7.mol

Synonyms:2,4-dichloro-6-(4-fluorophenyl)pyrimidine;833472-84-7;Pyrimidine,2,4-dichloro-6-(4-fluorophenyl)-;SCHEMBL908398;DTXSID30469828;QQLFWYQWFPLRRS-UHFFFAOYSA-N;AKOS015049929;4-BROMO-BENZIMIDICACIDETHYLESTER;2,4-dichloro-6-(4-fluoro-phenyl)-pyrimidine;A1-21633;2,4-Dichloro-6-(4-fluorophenyl)pyrimidine, AldrichCPR

Suppliers and Price of 2,4-Dichloro-6-(4-fluorophenyl)pyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2,4-DICHLORO-6-(4-FLUOROPHENYL)PYRIMIDINE 95.00%
5MG
$ 501.75

A1 Biochem Labs
2,4-Dichloro-6-(4-fluorophenyl)pyrimidine 95%
2.5 g
$ 1300.00

Total 5 raw suppliers

Chemical Property of 2,4-Dichloro-6-(4-fluorophenyl)pyrimidine

Chemical Property:

PSA：25.78000
LogP:3.58950
XLogP3:3.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:241.9813817
Heavy Atom Count:15
Complexity:210

Purity/Quality:

98%+ ^*data from raw suppliers

2,4-DICHLORO-6-(4-FLUOROPHENYL)PYRIMIDINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C2=CC(=NC(=N2)Cl)Cl)F

Technology Process of 2,4-Dichloro-6-(4-fluorophenyl)pyrimidine

There total 6 articles about 2,4-Dichloro-6-(4-fluorophenyl)pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 3764-01-0
2,4,6-trichloropyrimidine

: 1765-93-1
4-fluoroboronic acid

: 833472-84-7
2,4-dichloro-6-(4-fluorophenyl)pyrimidine

Guidance literature:: With palladium diacetate; sodium carbonate; triphenylphosphine; In tetrahydrofuran; water; at 60 ℃; for 6h; Inert atmosphere;

Reference yield: 90.0%

: 3764-01-0
2,4,6-trichloropyrimidine

: 1765-93-1
4-fluoroboronic acid

: 603-35-0
triphenylphosphine

: 833472-84-7
2,4-dichloro-6-(4-fluorophenyl)pyrimidine

: 2C₁₈H₁₅P*C₄HCl₃N₂Pd

Guidance literature:: With palladium diacetate; sodium carbonate; In tetrahydrofuran; at 60 ℃; for 3h;
DOI:10.1021/ol052578p

Reference yield:

: 3934-20-1
2,6-Dichloropyrimidine

: 833472-84-7
2,4-dichloro-6-(4-fluorophenyl)pyrimidine

Guidance literature:: 1-Bromo-4-fluorobenzene; With n-butyllithium; In diethyl ether; at -78 ℃; for 0.75h;

2,6-Dichloropyrimidine; In diethyl ether; at -78 - 0 ℃; for 1h;

With sodium hydroxide; water; acetic acid; 2,3-dicyano-5,6-dichloro-p-benzoquinone; more than 3 stages;