2-(N-methoxycarbonylpyrrolidin-2-yl)-4,6-di-tert-butylphenol

Base Information

• Chemical Name: 2-(N-methoxycarbonylpyrrolidin-2-yl)-4,6-di-tert-butylphenol
• CAS No.: 340228-48-0
• Molecular Formula: C₂₀H₃₁NO₃
• Molecular Weight: 333.471
• Mol file: 340228-48-0.mol

Synonyms:2-(N-methoxycarbonylpyrrolidin-2-yl)-4,6-di-tert-butylphenol

Chemical Property of 2-(N-methoxycarbonylpyrrolidin-2-yl)-4,6-di-tert-butylphenol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(N-methoxycarbonylpyrrolidin-2-yl)-4,6-di-tert-butylphenol

There total 1 articles about 2-(N-methoxycarbonylpyrrolidin-2-yl)-4,6-di-tert-butylphenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,4-di-tert-Butylphenol (96-76-4) + methyl 2-methoxypyrrolidine-1-carboxylate (56475-88-8) → 2-(N-methoxycarbonylpyrrolidin-2-yl)-4,6-di-tert-butylphenol (340228-48-0)

Guidance literature:

methyl 2-methoxypyrrolidine-1-carboxylate; With titanium tetrachloride; In dichloromethane; at -78 ℃; for 0.5h;

2,4-di-tert-Butylphenol; In dichloromethane; at 20 ℃; for 5h; Further stages.;

DOI:10.1021/ja002453+

Reference yield:

2-(N-methoxycarbonylpyrrolidin-2-yl)-4,6-di-tert-butylphenol (340228-48-0) + chloromethyl methyl ether (107-30-2) → 2-(3,5-di-tert-butyl-2-methoxymethoxy-phenyl)-pyrrolidine-1-carboxylic acid methyl ester (340228-50-4)

Guidance literature:

2-(N-methoxycarbonylpyrrolidin-2-yl)-4,6-di-tert-butylphenol; With sodium hydride; In tetrahydrofuran; at 0 ℃; for 0.5h;

chloromethyl methyl ether; In tetrahydrofuran; at 20 ℃; Further stages.;

DOI:10.1021/ja002453+

Reference yield:

2-(N-methoxycarbonylpyrrolidin-2-yl)-4,6-di-tert-butylphenol (340228-48-0) → 2,4-di-tert-butyl-6-(1-methyl-2-pyrrolidino)phenol (340228-43-5)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; for 6h; Heating;

DOI:10.1021/ja002453+

upstream raw materials:

2,4-di-tert-Butylphenol

methyl 2-methoxypyrrolidine-1-carboxylate

Downstream raw materials:

2,4-di-tert-butyl-6-(1-methyl-2-pyrrolidino)phenol

2-(3,5-di-tert-butyl-2-methoxymethoxy-phenyl)-pyrrolidine-1-carboxylic acid methyl ester

2-(3,5-di-tert-butyl-2-methoxymethoxy-phenyl)-1-methyl-pyrrolidine