1-(4-Fluorophenyl)-1,1-dimethylsilanol

Base Information

Chemical Name:1-(4-Fluorophenyl)-1,1-dimethylsilanol
CAS No.:22868-28-6
Molecular Formula:C₈H₁₁FOSi
Molecular Weight:170.259
Hs Code.:
DSSTox Substance ID:DTXSID701284999
Nikkaji Number:J1.979.470I

Synonyms:DTXSID701284999;1-(4-Fluorophenyl)-1,1-dimethylsilanol

Suppliers and Price of 1-(4-Fluorophenyl)-1,1-dimethylsilanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-(4-Fluorophenyl)-1,1-dimethylsilanol

Chemical Property:

Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:170.05631967
Heavy Atom Count:11
Complexity:130

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C[Si](C)(C1=CC=C(C=C1)F)O

Technology Process of 1-(4-Fluorophenyl)-1,1-dimethylsilanol

There total 5 articles about 1-(4-Fluorophenyl)-1,1-dimethylsilanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 1432-40-2
(4-fluorophenyl)dimethylsilane

: 22868-28-6
4-fluorophenyl(dimethyl)silanol

Guidance literature:: With [RhCl₂(p-cymene)]2; water; In acetonitrile; for 0.000555556 - 0.000833333h;
DOI:10.1021/jacs.7b00357

Reference yield: 79.0%

: 541-05-9
Hexamethylcyclotrisiloxane

: 460-00-4
1-Bromo-4-fluorobenzene

: 22868-28-6
4-fluorophenyl(dimethyl)silanol

Guidance literature:: 1-Bromo-4-fluorobenzene; With tert.-butyl lithium; In diethyl ether; at -78 ℃; Inert atmosphere;

Hexamethylcyclotrisiloxane; In diethyl ether; at -78 - 20 ℃; Inert atmosphere;
DOI:10.1021/ja8091449

Reference yield:

: 56633-16-0
1,1-dimethylphenylmethylsilanol

: 2355-86-4
(4-fluorophenyl)chlorodimethylsilane

: 1833-31-4
benzyl(chloro)dimethylsilane

: 22868-28-6
4-fluorophenyl(dimethyl)silanol

: 1833-27-8
1,3-Dibenzyltetramethyldisiloxane

: 845-96-5
1,3-bis(4′-fluorophenyl)-1,1,3,3-tetramethyldisiloxane

: 1-Benzyl-3-(4-fluoro-phenyl)-1,1,3,3-tetramethyl-disiloxane

Guidance literature:: With water; In 1,4-dioxane; benzene-d6; at 30 ℃; Product distribution; Rate constant; var. concn. of H₂O;
DOI:10.1016/0022-328X(88)80671-5