2-Acetamido-3-(2,4-difluorophenyl)prop-2-enoic acid

Base Information

Chemical Name:2-Acetamido-3-(2,4-difluorophenyl)prop-2-enoic acid
CAS No.:831191-80-1
Molecular Formula:C11H9 F2 N O3
Molecular Weight:241.19
Hs Code.:2924299090
DSSTox Substance ID:DTXSID90698455
Mol file:831191-80-1.mol

Synonyms:831191-80-1;2-Acetamido-3-(2,4-difluorophenyl)prop-2-enoic acid;DTXSID90698455

Suppliers and Price of 2-Acetamido-3-(2,4-difluorophenyl)prop-2-enoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-ACETYLAMINO-3-(2,4-DIFLUOROPHENYL)ACRYLIC ACID 95.00%
5MG
$ 501.70

Total 3 raw suppliers

Chemical Property of 2-Acetamido-3-(2,4-difluorophenyl)prop-2-enoic acid

Chemical Property:

PSA：66.40000
LogP:1.91730
XLogP3:1.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:241.05504947
Heavy Atom Count:17
Complexity:344

Purity/Quality:

99%+ ^*data from raw suppliers

2-ACETYLAMINO-3-(2,4-DIFLUOROPHENYL)ACRYLIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)NC(=CC1=C(C=C(C=C1)F)F)C(=O)O

Technology Process of 2-Acetamido-3-(2,4-difluorophenyl)prop-2-enoic acid

There total 2 articles about 2-Acetamido-3-(2,4-difluorophenyl)prop-2-enoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.6%

: 831191-79-8
4-[1-(2,4-Difluoro-phenyl)-meth-(Z)-ylidene]-2-methyl-4H-oxazol-5-one

: 831191-80-1
2-acetylamino-3-(2,4-difluorophenyl)acrylic acid

Guidance literature:: In water; acetone; for 4h; Heating;
DOI:10.3390/90600405

Reference yield:

: 1550-35-2
2,4-difluorobenzaldehyde

: 831191-80-1
2-acetylamino-3-(2,4-difluorophenyl)acrylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 69 percent / Ac₂O; NaOAc / 1 h / Heating

2: 75.6 percent / acetone; H₂O / 4 h / Heating

With sodium acetate; acetic anhydride; In water; acetone; 1: Erlenmeyer reaction;
DOI:10.3390/90600405