2-(RS)-{2-[(1H-indole-2-carbonyl)amino]benzoylamino}succinic acid diethyl ester

Base Information

Chemical Name:2-(RS)-{2-[(1H-indole-2-carbonyl)amino]benzoylamino}succinic acid diethyl ester
CAS No.:1155261-46-3
Molecular Formula:C₂₄H₂₅N₃O₆
Molecular Weight:451.479
Hs Code.:

Synonyms:2-(RS)-{2-[(1H-indole-2-carbonyl)amino]benzoylamino}succinic acid diethyl ester

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Chemical Property of 2-(RS)-{2-[(1H-indole-2-carbonyl)amino]benzoylamino}succinic acid diethyl ester

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Technology Process of 2-(RS)-{2-[(1H-indole-2-carbonyl)amino]benzoylamino}succinic acid diethyl ester

There total 1 articles about 2-(RS)-{2-[(1H-indole-2-carbonyl)amino]benzoylamino}succinic acid diethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

Indole-2-carboxylic acid: 1477-50-5,1228050-17-6
Indole-2-carboxylic acid

: 296282-28-5
2-(RS)-(2-aminobenzoylamino)succinic acid diethyl ester

: 1155261-46-3
2-(RS)-{2-[(1H-indole-2-carbonyl)amino]benzoylamino}succinic acid diethyl ester

Guidance literature:: Indole-2-carboxylic acid; With phosphorus pentachloride; acetyl chloride; at 20 ℃; for 3.5h; Cooling with ice;

2-(RS)-(2-aminobenzoylamino)succinic acid diethyl ester; With pyridine; In dichloromethane; at 0 - 20 ℃;
DOI:10.1016/j.bmc.2009.02.012

Reference yield: 28.0%

: 1155261-46-3
2-(RS)-{2-[(1H-indole-2-carbonyl)amino]benzoylamino}succinic acid diethyl ester

: 1155261-65-6
2-(RS)-{2-[(1H-indole-2-carbonyl)amino]benzoylamino}succinic acid

Guidance literature:: 2-(RS)-{2-[(1H-indole-2-carbonyl)amino]benzoylamino}succinic acid diethyl ester; With potassium hydroxide; water; In tetrahydrofuran; at 20 ℃;

With hydrogenchloride; In water; at 0 ℃; pH=2 - 3;
DOI:10.1016/j.bmc.2009.02.012