3-(4-benzyl-[1,2,3]triazol-1-yl)-2-tert-butoxycarbonylamino-propionic acid

Base Information

• Chemical Name: 3-(4-benzyl-[1,2,3]triazol-1-yl)-2-tert-butoxycarbonylamino-propionic acid
• CAS No.: 928838-57-7
• Molecular Formula: C₁₇H₂₂N₄O₄
• Molecular Weight: 346.386
• Mol file: 928838-57-7.mol

Synonyms:3-(4-benzyl-[1,2,3]triazol-1-yl)-2-tert-butoxycarbonylamino-propionic acid

Chemical Property of 3-(4-benzyl-[1,2,3]triazol-1-yl)-2-tert-butoxycarbonylamino-propionic acid

Chemical Property:

Purity/Quality:

Safty Information:

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Technology Process of 3-(4-benzyl-[1,2,3]triazol-1-yl)-2-tert-butoxycarbonylamino-propionic acid

There total 1 articles about 3-(4-benzyl-[1,2,3]triazol-1-yl)-2-tert-butoxycarbonylamino-propionic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

propargyl benzene (10147-11-2) + (S)-3-azido-2-((tert-butoxycarbonyl)amino)propanoic acid (122225-54-1,108283-49-4) → 3-(4-benzyl-[1,2,3]triazol-1-yl)-2-tert-butoxycarbonylamino-propionic acid (928838-57-7)

Guidance literature:

With sodium L-ascorbate; copper diacetate; In water; tert-butyl alcohol; at 20 ℃;

DOI:10.1021/ja066779f

Reference yield: 93.0%

3-(4-benzyl-[1,2,3]triazol-1-yl)-2-tert-butoxycarbonylamino-propionic acid (928838-57-7) → 2-amino-3-(4-benzyl-[1,2,3]triazol-1-yl)-propionic acid

Guidance literature:

With trifluoroacetic acid; In dichloromethane;

Reference yield: 93.0%

3-(4-benzyl-[1,2,3]triazol-1-yl)-2-tert-butoxycarbonylamino-propionic acid (928838-57-7) + trifluoroacetic acid (76-05-1) → 2-amino-3-(4-benzyl-[1,2,3]triazol-1-yl)-propionic acid; compound with trifluoro-acetic acid

Guidance literature:

In dichloromethane; at 20 ℃;

DOI:10.1021/ja066779f

upstream raw materials:

propargyl benzene

(S)-3-azido-2-((tert-butoxycarbonyl)amino)propanoic acid