ethyl 4-(4-chlorophenyl)-3-cyano-2,3'-bithiophene-5-carboxylate

Base Information

• Chemical Name: ethyl 4-(4-chlorophenyl)-3-cyano-2,3'-bithiophene-5-carboxylate
• CAS No.: 1322757-91-4
• Molecular Formula: C₁₈H₁₂ClNO₂S₂
• Molecular Weight: 373.884
• Mol file: 1322757-91-4.mol

Synonyms:ethyl 4-(4-chlorophenyl)-3-cyano-2,3'-bithiophene-5-carboxylate

Chemical Property of ethyl 4-(4-chlorophenyl)-3-cyano-2,3'-bithiophene-5-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of ethyl 4-(4-chlorophenyl)-3-cyano-2,3'-bithiophene-5-carboxylate

There total 1 articles about ethyl 4-(4-chlorophenyl)-3-cyano-2,3'-bithiophene-5-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

Thien-3-ylboronic acid (6165-69-1) + C17H16ClNO2S2 (882278-95-7) → ethyl 4-(4-chlorophenyl)-3-cyano-2,3'-bithiophene-5-carboxylate (1322757-91-4)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; copper(I) thiophene-2-carboxylate; In tetrahydrofuran; at 50 ℃; for 48h; Inert atmosphere;

DOI:10.1002/ejoc.201100215

Reference yield: 100.0%

ethyl 4-(4-chlorophenyl)-3-cyano-2,3'-bithiophene-5-carboxylate (1322757-91-4) → 4-(4-chlorophenyl)-3-cyano-2,3'-bithiophene-5-carboxylic acid (1322758-19-9)

Guidance literature:

With water; sodium hydroxide; In tetrahydrofuran; ethanol; at 20 ℃; for 16h; Inert atmosphere;

DOI:10.1002/ejoc.201100215

upstream raw materials:

Thien-3-ylboronic acid

C₁₇H₁₆ClNO₂S₂

Downstream raw materials:

4-(4-chlorophenyl)-3-cyano-2,3'-bithiophene-5-carboxylic acid