(R)-(-)-1-phenyl-2-aminopropane sulfate

Base Information

• Chemical Name: (R)-(-)-1-phenyl-2-aminopropane sulfate
• CAS No.: 171501-68-1
• Molecular Formula: C₉H₁₃N*H₂O₄S
• Molecular Weight: 233.288

Synonyms:(R)-(-)-1-phenyl-2-aminopropane sulfate

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Chemical Property of (R)-(-)-1-phenyl-2-aminopropane sulfate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (R)-(-)-1-phenyl-2-aminopropane sulfate

There total 1 articles about (R)-(-)-1-phenyl-2-aminopropane sulfate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

amphetamine sulfate (62306-10-9) → (R)-(-)-1-phenyl-2-aminopropane sulfate (171501-68-1) + D-amphetamine sulfate (17279-36-6)

Guidance literature:

With chiral stationary phase including isopropyl-functionalized CF₆; In methanol; acetic acid; triethylamine; acetonitrile; at 20 ℃; Purification / work up;

Reference yield: 50.6%

(R)-(-)-1-phenyl-2-aminopropane sulfate (171501-68-1) + 1,1'-carbonyldiimidazole (530-62-1) + eseroline (469-22-7) → C23H29N3O2 (851086-89-0)

Guidance literature:

1,1'-carbonyldiimidazole; eseroline; In ethyl acetate; at 20 ℃; for 2h;

(R)-(-)-1-phenyl-2-aminopropane sulfate; With acetic acid; In ethyl acetate; at 20 ℃; for 24h;

Reference yield: 39.0%

(R)-(-)-1-phenyl-2-aminopropane sulfate (171501-68-1) + (S)-3-(1-dimethylaminoethyl)phenol (139306-10-8) + 1,1'-carbonyldiimidazole (530-62-1) → S-rivastigmine-l-amphetamine (851086-86-7)

Guidance literature:

(S)-3-(1-dimethylaminoethyl)phenol; 1,1'-carbonyldiimidazole; In ethyl acetate; at 85 ℃;

(R)-(-)-1-phenyl-2-aminopropane sulfate; With acetic acid;

In ethyl acetate; at 20 ℃; for 36h; Product distribution / selectivity;

upstream raw materials:

amphetamine sulfate

Downstream raw materials:

(R)-(-)-1-phenyl-2-benzylaminopropane

(-)-N-Ethylamphetamine

((R)-1-Methyl-2-phenyl-ethyl)-propyl-amine

benzyl-(1-methyl-2-phenyl-ethyl)-amine; hydrochloride