(R)-N-[(R)-(4-chlorophenyl)(2-methoxynaphthalen-1-yl)methyl]-1-phenylethanamine

Base Information

Chemical Name:(R)-N-[(R)-(4-chlorophenyl)(2-methoxynaphthalen-1-yl)methyl]-1-phenylethanamine
CAS No.:1033590-57-6
Molecular Formula:C₂₆H₂₄ClNO
Molecular Weight:401.936
Hs Code.:

Synonyms:(R)-N-[(R)-(4-chlorophenyl)(2-methoxynaphthalen-1-yl)methyl]-1-phenylethanamine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R)-N-[(R)-(4-chlorophenyl)(2-methoxynaphthalen-1-yl)methyl]-1-phenylethanamine

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Technology Process of (R)-N-[(R)-(4-chlorophenyl)(2-methoxynaphthalen-1-yl)methyl]-1-phenylethanamine

There total 1 articles about (R)-N-[(R)-(4-chlorophenyl)(2-methoxynaphthalen-1-yl)methyl]-1-phenylethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 1033590-52-1
benzyl [(R)-(4-chlorophenyl)(2-methoxynaphthalen-1-yl)methyl][(R)-1-phenylethyl]carbamate

: 1033590-57-6
(R)-N-[(R)-(4-chlorophenyl)(2-methoxynaphthalen-1-yl)methyl]-1-phenylethanamine

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol;
DOI:10.1055/s-2008-1032199

Reference yield: 48.0%

: 1033590-57-6
(R)-N-[(R)-(4-chlorophenyl)(2-methoxynaphthalen-1-yl)methyl]-1-phenylethanamine

: 18531-99-2
(S)-[1,1']-binaphthalenyl-2,2'-diol

: [(S)-1,1'-dinaphthyl-2,2'-diyl] [(R)-(4-chlorophenyl)(2-methoxynaphthalen-1-yl)methyl][(R)-1-phenylethyl]phosphoramidite

Guidance literature:: (R)-N-[(R)-(4-chlorophenyl)(2-methoxynaphthalen-1-yl)methyl]-1-phenylethanamine; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h;

With phosphorus trichloride; In tetrahydrofuran; hexane; at 0 ℃; for 3h;

(S)-[1,1']-binaphthalenyl-2,2'-diol; With triethylammonium iodide; In tetrahydrofuran; hexane; at 20 ℃; for 12h; Further stages.;
DOI:10.1055/s-2008-1032199

Reference yield: 32.0%

: 1033590-57-6
(R)-N-[(R)-(4-chlorophenyl)(2-methoxynaphthalen-1-yl)methyl]-1-phenylethanamine

: 18531-94-7
(R)-1,1'-Bi-2-naphthol

: [(R)-1,1'-dinaphthyl-2,2'-diyl] [(R)-(4-chlorophenyl)(2-methoxynaphthalen-1-yl)methyl][(R)-1-phenylethyl]phosphoramidite

Guidance literature:: (R)-N-[(R)-(4-chlorophenyl)(2-methoxynaphthalen-1-yl)methyl]-1-phenylethanamine; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h;

With phosphorus trichloride; In tetrahydrofuran; hexane; at 0 ℃; for 3h;

(R)-1,1'-Bi-2-naphthol; With triethylammonium iodide; In tetrahydrofuran; hexane; at 20 ℃; for 12h; Further stages.;
DOI:10.1055/s-2008-1032199