(S)-benzyl (4-(3-methoxypyrrolidin-1-yl)cyclohexyl)carbamate

Base Information

• Chemical Name: (S)-benzyl (4-(3-methoxypyrrolidin-1-yl)cyclohexyl)carbamate
• CAS No.: 1378308-05-4
• Molecular Formula: C₁₉H₂₈N₂O₃
• Molecular Weight: 332.443
• Mol file: 1378308-05-4.mol

Synonyms:(S)-benzyl (4-(3-methoxypyrrolidin-1-yl)cyclohexyl)carbamate

Chemical Property of (S)-benzyl (4-(3-methoxypyrrolidin-1-yl)cyclohexyl)carbamate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of (S)-benzyl (4-(3-methoxypyrrolidin-1-yl)cyclohexyl)carbamate

There total 1 articles about (S)-benzyl (4-(3-methoxypyrrolidin-1-yl)cyclohexyl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

benzyl N-(4-oxocyclohexyl)carbamate (16801-63-1) + (S)-3-methoxy-pyrrolidine (120099-61-8) → (S)-benzyl (4-(3-methoxypyrrolidin-1-yl)cyclohexyl)carbamate (1378308-05-4)

Guidance literature:

With sodium tris(acetoxy)borohydride; In 1,2-dichloro-ethane; at 20 ℃; for 18h;

Reference yield:

(S)-benzyl (4-(3-methoxypyrrolidin-1-yl)cyclohexyl)carbamate (1378308-05-4) → (S)-4-(3-methoxypyrrolidin-1-yl)cyclohexanamine (1378308-06-5)

Guidance literature:

With hydrogen; palladium 10% on activated carbon; In ethanol; at 25 ℃; for 16h;

upstream raw materials:

benzyl N-(4-oxocyclohexyl)carbamate

(S)-3-methoxy-pyrrolidine

Downstream raw materials:

(S)-4-(3-methoxypyrrolidin-1-yl)cyclohexanamine