Carbonic acid benzyl ester 3,5-dioxo-10-oxa-4-aza-tricyclo[5.2.1.0^2,6]dec-8-en-4-yl ester

Base Information

• Chemical Name: Carbonic acid benzyl ester 3,5-dioxo-10-oxa-4-aza-tricyclo[5.2.1.0^2,6]dec-8-en-4-yl ester
• CAS No.: 58936-18-8
• Molecular Formula: C₁₆H₁₃NO₆
• Molecular Weight: 315.282
• Mol file: 58936-18-8.mol

Synonyms:Carbonic acid benzyl ester 3,5-dioxo-10-oxa-4-aza-tricyclo[5.2.1.0^2,6]dec-8-en-4-yl ester

Chemical Property of Carbonic acid benzyl ester 3,5-dioxo-10-oxa-4-aza-tricyclo[5.2.1.0^2,6]dec-8-en-4-yl ester

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of Carbonic acid benzyl ester 3,5-dioxo-10-oxa-4-aza-tricyclo[5.2.1.0^2,6]dec-8-en-4-yl ester

There total 1 articles about Carbonic acid benzyl ester 3,5-dioxo-10-oxa-4-aza-tricyclo[5.2.1.0^2,6]dec-8-en-4-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

benzyl chloroformate (501-53-1,94274-21-2) + exo‐N‐hydroxy‐7‐oxabicyclo[2.2.1]hept‐5‐ene‐2,3‐dicarboximide (5596-17-8,146985-80-0) → Carbonic acid benzyl ester 3,5-dioxo-10-oxa-4-aza-tricyclo[5.2.1.02,6]dec-8-en-4-yl ester (58936-18-8)

Guidance literature:

With triethylamine; In N,N-dimethyl-formamide; for 2h; Ambient temperature;

Reference yield: 83.0%

Carbonic acid benzyl ester 3,5-dioxo-10-oxa-4-aza-tricyclo[5.2.1.02,6]dec-8-en-4-yl ester (58936-18-8) → benzyl N-maleimidyl carbonate (58936-19-9)

Guidance literature:

With 3-tert-butylbenzene-1,2-diol; In nitrobenzene; at 155 - 160 ℃; for 0.5h; under 100 Torr;

upstream raw materials:

benzyl chloroformate

exo‐N‐hydroxy‐7‐oxabicyclo[2.2.1]hept‐5‐ene‐2,3‐dicarboximide

Downstream raw materials:

benzyl N-maleimidyl carbonate