C₂₁H₂₂O₅S

Base Information

Chemical Name:C₂₁H₂₂O₅S
CAS No.:211799-89-2
Molecular Formula:C₂₁H₂₂O₅S
Molecular Weight:386.469
Hs Code.:

C<sub>21</sub>H<sub>22</sub>O<sub>5</sub>S

Synonyms:C₂₁H₂₂O₅S

Suppliers and Price of C₂₁H₂₂O₅S

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of C₂₁H₂₂O₅S

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of C₂₁H₂₂O₅S

There total 24 articles about C₂₁H₂₂O₅S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 108-98-5
thiophenol

: 211799-86-9
C₁₅H₁₈O₆

: 211799-89-2
C₂₁H₂₂O₅S

Guidance literature:: With chloro-trimethyl-silane; In acetonitrile; Ambient temperature;
DOI:10.1021/ja953060r

Reference yield:

: 6485-40-1,2244-16-8
(R)-Carvone

: 211799-89-2
C₂₁H₂₂O₅S

Guidance literature:: Multi-step reaction with 24 steps

1: 64 percent / LDA / tetrahydrofuran / -78 °C

2: 95 percent / C₃H₄N₂ / dimethylformamide / 60 °C

3: 73 percent / tetrahydrofuran / -78 °C

4: 96 percent / C₅H₅N⁽¹⁺⁾*HBr₃^(1-), C₅H₅N / 0 °C

5: 1.) DIBAL-H / 1.) toluene, -78 deg C, 2.) THF, 0 deg C

6: C₃H₄N₂ / dimethylformamide / 60 °C

7: 70 percent / 1,3-di(9-phosphafluoren-9-yl)propane, 2-(diphenylphosphino)benzoic acid, palladium acetate / 1,2-dichloro-ethane / 60 °C

8: 89 percent / TBAF / tetrahydrofuran / Ambient temperature

9: 1.) SOCl₂, 2.) CsOAc, 3.) K₂CO₃

10: 1.) (COCl)2, (C₂H₅)3N, 2.) NaClO₂, (CH₃)2C=CHCH₃, NaH₂PO₄

11: 63 percent / CF₃CO₃H, CSA / CH₂Cl₂ / Heating

12: 75 percent / OsO₄, C₅H₅N / Ambient temperature

13: 96 percent / Zn, HOAc / methanol / 60 °C

14: 70 percent / TsOH / acetone

15: 1.) aq. KOH / 1.) CH₃OH, RT, 2.) ether, 0 deg C

16: 86 percent / (C₂H₅)3N, DMAP / CH₂Cl₂

17: 67 percent / aq. HCl / tetrahydrofuran / Ambient temperature

18: 85 percent / lutidine / 1,2-dichloro-ethane / Ambient temperature

19: 90 percent / NaCN / methanol; tetrahydrofuran / Ambient temperature

20: 68 percent / t-C₄H₉OLi, t-C₄H₉OH / toluene / 100 °C

21: 92 percent / aq. HF / acetonitrile / 100 °C

22: 85 percent / (CF₃SO₂)2O, N-methylimidazole / 100 °C

23: 71 percent / LiBH₄, HOAc / tetrahydrofuran / 0 °C

24: 98 percent / TMS-Cl / acetonitrile / Ambient temperature

With pyridine; 1-methyl-1H-imidazole; hydrogenchloride; dmap; potassium hydroxide; sodium chlorite; sodium dihydrogenphosphate; osmium(VIII) oxide; lithium borohydride; chloro-trimethyl-silane; thionyl chloride; 2-methyl-but-2-ene; oxalyl dichloride; trifluoromethylsulfonic anhydride; trifluoroacetyl peroxide; 1,3-di(9-phosphafluoren-9-yl)propane; lutidine; camphor-10-sulfonic acid; ortho-diphenylphosphinobenzoic acid; hydrogen fluoride; sodium cyanide; tetrabutyl ammonium fluoride; cesium acetate; palladium diacetate; diisobutylaluminium hydride; potassium carbonate; toluene-4-sulfonic acid; acetic acid; pyridinium hydrobromide perbromide; triethylamine; lithium tert-butoxide; zinc; tert-butyl alcohol; lithium diisopropyl amide; In tetrahydrofuran; methanol; dichloromethane; 1,2-dichloro-ethane; N,N-dimethyl-formamide; acetone; toluene; acetonitrile;
DOI:10.1021/ja953060r

Reference yield:

: 172277-78-0
(5R,6R)-6-(hydroxymethyl)-2-methyl-5-(1-methylethenyl)-2-cyclohexen-1-one

: 211799-89-2
C₂₁H₂₂O₅S

Guidance literature:: Multi-step reaction with 23 steps

1: 95 percent / C₃H₄N₂ / dimethylformamide / 60 °C

2: 73 percent / tetrahydrofuran / -78 °C

3: 96 percent / C₅H₅N⁽¹⁺⁾*HBr₃^(1-), C₅H₅N / 0 °C

4: 1.) DIBAL-H / 1.) toluene, -78 deg C, 2.) THF, 0 deg C

5: C₃H₄N₂ / dimethylformamide / 60 °C

6: 70 percent / 1,3-di(9-phosphafluoren-9-yl)propane, 2-(diphenylphosphino)benzoic acid, palladium acetate / 1,2-dichloro-ethane / 60 °C

7: 89 percent / TBAF / tetrahydrofuran / Ambient temperature

8: 1.) SOCl₂, 2.) CsOAc, 3.) K₂CO₃

9: 1.) (COCl)2, (C₂H₅)3N, 2.) NaClO₂, (CH₃)2C=CHCH₃, NaH₂PO₄

10: 63 percent / CF₃CO₃H, CSA / CH₂Cl₂ / Heating

11: 75 percent / OsO₄, C₅H₅N / Ambient temperature

12: 96 percent / Zn, HOAc / methanol / 60 °C

13: 70 percent / TsOH / acetone

14: 1.) aq. KOH / 1.) CH₃OH, RT, 2.) ether, 0 deg C

15: 86 percent / (C₂H₅)3N, DMAP / CH₂Cl₂

16: 67 percent / aq. HCl / tetrahydrofuran / Ambient temperature

17: 85 percent / lutidine / 1,2-dichloro-ethane / Ambient temperature

18: 90 percent / NaCN / methanol; tetrahydrofuran / Ambient temperature

19: 68 percent / t-C₄H₉OLi, t-C₄H₉OH / toluene / 100 °C

20: 92 percent / aq. HF / acetonitrile / 100 °C

21: 85 percent / (CF₃SO₂)2O, N-methylimidazole / 100 °C

22: 71 percent / LiBH₄, HOAc / tetrahydrofuran / 0 °C

23: 98 percent / TMS-Cl / acetonitrile / Ambient temperature

With pyridine; 1-methyl-1H-imidazole; hydrogenchloride; dmap; potassium hydroxide; sodium chlorite; sodium dihydrogenphosphate; osmium(VIII) oxide; lithium borohydride; chloro-trimethyl-silane; thionyl chloride; 2-methyl-but-2-ene; oxalyl dichloride; trifluoromethylsulfonic anhydride; trifluoroacetyl peroxide; 1,3-di(9-phosphafluoren-9-yl)propane; lutidine; camphor-10-sulfonic acid; ortho-diphenylphosphinobenzoic acid; hydrogen fluoride; sodium cyanide; tetrabutyl ammonium fluoride; cesium acetate; palladium diacetate; diisobutylaluminium hydride; potassium carbonate; toluene-4-sulfonic acid; acetic acid; pyridinium hydrobromide perbromide; triethylamine; lithium tert-butoxide; zinc; tert-butyl alcohol; In tetrahydrofuran; methanol; dichloromethane; 1,2-dichloro-ethane; N,N-dimethyl-formamide; acetone; toluene; acetonitrile;
DOI:10.1021/ja953060r