2,2'-[(E)-1,2-ethenediyl]bis[5-aminobenzenesulfonic acid], bis(1-methylethyl) ester

Base Information

• Chemical Name: 2,2'-[(E)-1,2-ethenediyl]bis[5-aminobenzenesulfonic acid], bis(1-methylethyl) ester
• CAS No.: 299181-84-3
• Molecular Formula: C₂₀H₂₆N₂O₆S₂
• Molecular Weight: 454.568
• Mol file: 299181-84-3.mol

Synonyms:2,2'-[(E)-1,2-ethenediyl]bis[5-aminobenzenesulfonic acid], bis(1-methylethyl) ester

Chemical Property of 2,2'-[(E)-1,2-ethenediyl]bis[5-aminobenzenesulfonic acid], bis(1-methylethyl) ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,2'-[(E)-1,2-ethenediyl]bis[5-aminobenzenesulfonic acid], bis(1-methylethyl) ester

There total 3 articles about 2,2'-[(E)-1,2-ethenediyl]bis[5-aminobenzenesulfonic acid], bis(1-methylethyl) ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

2,2'-[(E)-1,2-ethenediyl]bis(5-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}benzenesulfonic acid) bis(1-methylethyl) ester (299181-83-2) → 2,2'-[(E)-1,2-ethenediyl]bis[5-aminobenzenesulfonic acid], bis(1-methylethyl) ester (299181-84-3)

Guidance literature:

With piperidine; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 3h;

DOI:10.1016/S0968-0896(01)00324-8

Reference yield:

trans-4,4'-diaminostilbene-2,2'-disulfonic acid (28096-93-7) → 2,2'-[(E)-1,2-ethenediyl]bis[5-aminobenzenesulfonic acid], bis(1-methylethyl) ester (299181-84-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 72 percent / sodium carbonate / dioxane

2: 75 percent / dioxane / Heating

3: 77 percent / piperidine / dimethylformamide / 3 h / 0 - 20 °C

With piperidine; sodium carbonate; In 1,4-dioxane; N,N-dimethyl-formamide;

DOI:10.1016/S0968-0896(01)00324-8

Reference yield:

2,2'-[(E)-1,2-ethenediyl]bis(5-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}benzenesulfonic acid) (299181-82-1) → 2,2'-[(E)-1,2-ethenediyl]bis[5-aminobenzenesulfonic acid], bis(1-methylethyl) ester (299181-84-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 75 percent / dioxane / Heating

2: 77 percent / piperidine / dimethylformamide / 3 h / 0 - 20 °C

With piperidine; In 1,4-dioxane; N,N-dimethyl-formamide;

DOI:10.1016/S0968-0896(01)00324-8

upstream raw materials:

2,2'-[(E)-1,2-ethenediyl]bis(5-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}benzenesulfonic acid) bis(1-methylethyl) ester

trans-4,4'-diaminostilbene-2,2'-disulfonic acid

2,2'-[(E)-1,2-ethenediyl]bis(5-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}benzenesulfonic acid)

Downstream raw materials:

5-[4-[(methylsulfonyl)-3-nitrobenzoyl]amino]-2-[(E)-2-[4-amino-2-sulfophenyl]ethenyl]benzenesulfonic acid, bis(1-methylethyl) ester

2-[(E)-2-[2-(isopropoxysulfonyl)-4-[4-(methylsulfonyl)-3-nitrobenzoyl]aminophenyl]ethenyl]-5-[4-[4-(methylthio)-3-(4-morpholinylsulfonyl)benzoyl]amino]benzenesulfonic acid, (1-methylethyl) ester

C₄₄H₅₂N₄O₁₈S₆

C₄₄H₅₂N₄O₁₄S₆