2-amino-4-(4'-bromophenyl)-3-cyano-4H,5H-pyrano[3,2-c][1]benzopyran-5-one

Base Information

• Chemical Name: 2-amino-4-(4'-bromophenyl)-3-cyano-4H,5H-pyrano[3,2-c][1]benzopyran-5-one
• CAS No.: 265109-09-9
• Molecular Formula: C₁₉H₁₁BrN₂O₃
• Molecular Weight: 395.212
• Mol file: 265109-09-9.mol

Synonyms:2-amino-4-(4'-bromophenyl)-3-cyano-4H,5H-pyrano[3,2-c][1]benzopyran-5-one

Chemical Property of 2-amino-4-(4'-bromophenyl)-3-cyano-4H,5H-pyrano[3,2-c][1]benzopyran-5-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of 2-amino-4-(4'-bromophenyl)-3-cyano-4H,5H-pyrano[3,2-c][1]benzopyran-5-one

There total 13 articles about 2-amino-4-(4'-bromophenyl)-3-cyano-4H,5H-pyrano[3,2-c][1]benzopyran-5-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

4-hydroxy[1]benzopyran-2-one (1076-38-6,92395-12-5) + 4-bromo-benzaldehyde (1122-91-4) + malononitrile (109-77-3) → 2-amino-4-(4'-bromophenyl)-3-cyano-4H,5H-pyrano[3,2-c][1]benzopyran-5-one (265109-09-9)

Guidance literature:

With sulfanilic acid-functionalized tris(hydroxymethyl) aminomethane-coated magnetite nanoparticles; In ethanol; water; at 70 ℃;

DOI:10.1007/s11164-019-04056-z

Reference yield: 97.0%

4-hydroxy[1]benzopyran-2-one (1076-38-6,92395-12-5) + 4-bromobenzenemethanol (873-75-6) + malononitrile (109-77-3) → 2-amino-4-(4'-bromophenyl)-3-cyano-4H,5H-pyrano[3,2-c][1]benzopyran-5-one (265109-09-9)

Guidance literature:

With dimethyl sulfoxide; 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide; In ethyl acetate; at 20 ℃; for 3.5h;

DOI:10.1371/journal.pone.0107118

Reference yield: 94.0%

4-hydroxy[1]benzopyran-2-one (1076-38-6,92395-12-5) + 4-bromobenzylidenemalononitrile (2826-24-6) → 2-amino-4-(4'-bromophenyl)-3-cyano-4H,5H-pyrano[3,2-c][1]benzopyran-5-one (265109-09-9)

Guidance literature:

With potassium fluoride; Montmorillonite; In N,N-dimethyl-formamide; at 90 ℃; for 6h;

DOI:10.3184/030823408X347585

upstream raw materials:

4-hydroxy[1]benzopyran-2-one

4-bromobenzylidenemalononitrile

4-bromo-benzaldehyde

malononitrile