Technology Process of bis[p-(2-{2-[2-(3-phenyl)ethoxy]ethoxy}ethoxy)benzyl]amine
There total 10 articles about bis[p-(2-{2-[2-(3-phenyl)ethoxy]ethoxy}ethoxy)benzyl]amine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
C53H71NO14;
With
hydrogenchloride;
In
methanol; water;
at 20 ℃;
Inert atmosphere;
With
trifluoroacetic acid;
In
methanol; chloroform; water;
at 20 ℃;
for 12h;
Inert atmosphere;
DOI:10.1002/ejoc.201101145
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: potassium carbonate / acetonitrile / Reflux; Inert atmosphere
2.1: magnesium sulfate; triethylamine / methanol / 10 h / 20 °C
2.2: 3.5 h / -5 - 0 °C
3.1: lithium aluminium tetrahydride / chloroform / 15 h / 20 °C / Cooling with ice
4.1: sodium hydroxide / tetrahydrofuran; water / 20 °C / Cooling with ice
5.1: caesium carbonate / acetonitrile / 24 h / 100 °C / Inert atmosphere
6.1: hydrogenchloride / methanol; water / 20 °C / Inert atmosphere
6.2: 12 h / 20 °C / Inert atmosphere
With
hydrogenchloride; lithium aluminium tetrahydride; magnesium sulfate; potassium carbonate; caesium carbonate; triethylamine; sodium hydroxide;
In
tetrahydrofuran; methanol; chloroform; water; acetonitrile;
DOI:10.1002/ejoc.201101145
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: lithium aluminium tetrahydride / chloroform / 15 h / 20 °C / Cooling with ice
2.1: sodium hydroxide / tetrahydrofuran; water / 20 °C / Cooling with ice
3.1: caesium carbonate / acetonitrile / 24 h / 100 °C / Inert atmosphere
4.1: hydrogenchloride / methanol; water / 20 °C / Inert atmosphere
4.2: 12 h / 20 °C / Inert atmosphere
With
hydrogenchloride; lithium aluminium tetrahydride; caesium carbonate; sodium hydroxide;
In
tetrahydrofuran; methanol; chloroform; water; acetonitrile;
DOI:10.1002/ejoc.201101145
