(Z)-2-(4-methoxybenzylidene)-3-oxo-2,3-dihydrobenzofuran-5-yl (9Z)-oleate

Base Information

• Chemical Name: (Z)-2-(4-methoxybenzylidene)-3-oxo-2,3-dihydrobenzofuran-5-yl (9Z)-oleate
• CAS No.: 1311271-73-4
• Molecular Formula: C₃₄H₄₄O₅
• Molecular Weight: 532.72
• Mol file: 1311271-73-4.mol

Synonyms:(Z)-2-(4-methoxybenzylidene)-3-oxo-2,3-dihydrobenzofuran-5-yl (9Z)-oleate

Chemical Property of (Z)-2-(4-methoxybenzylidene)-3-oxo-2,3-dihydrobenzofuran-5-yl (9Z)-oleate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (Z)-2-(4-methoxybenzylidene)-3-oxo-2,3-dihydrobenzofuran-5-yl (9Z)-oleate

There total 6 articles about (Z)-2-(4-methoxybenzylidene)-3-oxo-2,3-dihydrobenzofuran-5-yl (9Z)-oleate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.9%

(Z)-9-octadecenoyl chloride (112-77-6) + (Z)-5-hydroxy-2-(4-methoxybenzylidene)benzofuran-3(2H)-one (1234351-58-6) → (Z)-2-(4-methoxybenzylidene)-3-oxo-2,3-dihydrobenzofuran-5-yl (9Z)-oleate (1311271-73-4)

Guidance literature:

With pyridine; In dichloromethane; Reflux;

DOI:10.1016/j.bmc.2011.03.063

Reference yield:

2'-hydroxy-5'-(methoxymethoxy)-4-methoxychalcone (1311272-33-9) → (Z)-2-(4-methoxybenzylidene)-3-oxo-2,3-dihydrobenzofuran-5-yl (9Z)-oleate (1311271-73-4)

Guidance literature:

Multi-step reaction with 3 steps

1: pyridine; mercury(II) diacetate / 1 h / 110 °C

2: hydrogenchloride; water / methanol / 0.5 h / Reflux

3: pyridine / dichloromethane / Reflux

With pyridine; hydrogenchloride; mercury(II) diacetate; water; In methanol; dichloromethane;

DOI:10.1016/j.bmc.2011.03.063

Reference yield:

(Z)-2-(4-methoxybenzylidene)-5-(methoxymethoxy)benzo[b]furan-3-one (1311272-26-0) → (Z)-2-(4-methoxybenzylidene)-3-oxo-2,3-dihydrobenzofuran-5-yl (9Z)-oleate (1311271-73-4)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrogenchloride; water / methanol / 0.5 h / Reflux

2: pyridine / dichloromethane / Reflux

With pyridine; hydrogenchloride; water; In methanol; dichloromethane;

DOI:10.1016/j.bmc.2011.03.063

upstream raw materials:

(Z)-9-octadecenoyl chloride

(Z)-5-hydroxy-2-(4-methoxybenzylidene)benzofuran-3(2H)-one

2'-hydroxy-5'-(methoxymethoxy)-4-methoxychalcone

(Z)-2-(4-methoxybenzylidene)-5-(methoxymethoxy)benzo[b]furan-3-one