1,8-dihydroxy-10-<2-(3,4,5-trihydroxyphenyl)-1-oxoethyl>-9(10H)-anthracenone

Base Information

• Chemical Name: 1,8-dihydroxy-10-<2-(3,4,5-trihydroxyphenyl)-1-oxoethyl>-9(10H)-anthracenone
• CAS No.: 151562-59-3
• Molecular Formula: C₂₂H₁₆O₇
• Molecular Weight: 392.365
• Mol file: 151562-59-3.mol

Synonyms:1,8-dihydroxy-10-<2-(3,4,5-trihydroxyphenyl)-1-oxoethyl>-9(10H)-anthracenone

Chemical Property of 1,8-dihydroxy-10-<2-(3,4,5-trihydroxyphenyl)-1-oxoethyl>-9(10H)-anthracenone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,8-dihydroxy-10-<2-(3,4,5-trihydroxyphenyl)-1-oxoethyl>-9(10H)-anthracenone

There total 3 articles about 1,8-dihydroxy-10-<2-(3,4,5-trihydroxyphenyl)-1-oxoethyl>-9(10H)-anthracenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

1,8-Dihydroxy-10-[2-(3,4,5-tris-benzyloxy-phenyl)-acetyl]-10H-anthracen-9-one (151562-46-8) → 1,8-dihydroxy-10-<2-(3,4,5-trihydroxyphenyl)-1-oxoethyl>-9(10H)-anthracenone (151562-59-3)

Guidance literature:

With hydrogen; palladium on activated charcoal; In tetrahydrofuran; for 24h; under 760 Torr; Ambient temperature;

DOI:10.1021/jm00077a015

Reference yield: 80.0%

→ 1,8-dihydroxy-10-<2-(3,4,5-trihydroxyphenyl)-1-oxoethyl>-9(10H)-anthracenone (151562-59-3)

Guidance literature:

Reference yield:

(3,4,5-Tris-benzyloxy-phenyl)-acetyl chloride → 1,8-dihydroxy-10-<2-(3,4,5-trihydroxyphenyl)-1-oxoethyl>-9(10H)-anthracenone (151562-59-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 15 percent / pyridine / toluene / 3 h / Ambient temperature

2: 80 percent / H₂ / 10percent Pd/C / tetrahydrofuran / 24 h / 760 Torr / Ambient temperature

With pyridine; hydrogen; palladium on activated charcoal; In tetrahydrofuran; toluene;

DOI:10.1021/jm00077a015

upstream raw materials:

1,8-Dihydroxy-10-[2-(3,4,5-tris-benzyloxy-phenyl)-acetyl]-10H-anthracen-9-one

Downstream raw materials:

2-(3,4,5-trihydroxyphenyl)acetic acid

1-chloro-2-(3-(2-phenyl-ethyl)-2-benzofuryl)-ethane