2-methylsulfonylbenzaldehyde

Base Information

• Chemical Name: 2-methylsulfonylbenzaldehyde
• CAS No.: 5395-89-1
• Molecular Formula: C8H8O3S
• Molecular Weight: 184.216
• Hs Code.: 2913000090
• Mol file: 5395-89-1.mol

Synonyms:2-(Methylsulfonyl)benzaldehyde

Chemical Property of 2-methylsulfonylbenzaldehyde

Chemical Property:

• Vapor Pressure: 3.73E-06mmHg at 25°C
• Melting Point: 98-99 °C(Solv: water (7732-18-5))
• Refractive Index: 1.544
• Boiling Point: 385.7 °C at 760 mmHg
• Flash Point: 249.7 °C
• PSA: 59.59000
• Density: 1.289 g/cm³
• LogP: 1.98340

Purity/Quality:

99%, ^*data from raw suppliers

2-(Methylsulfonyl)benzaldehyde ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-methylsulfonylbenzaldehyde

There total 14 articles about 2-methylsulfonylbenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

methylsulfinic acid (17696-73-0) + 2-Fluorobenzaldehyde (446-52-6) → 2-methylsulphonylbenzaldehyde (5395-89-1)

Guidance literature:

In dimethyl sulfoxide; at 100 ℃; for 16h;

Reference yield:

o-Methylsulfon-phenylaethylenglykol (92474-86-7) → 2-methylsulphonylbenzaldehyde (5395-89-1)

Guidance literature:

With lead(IV) acetate; In benzene;

Reference yield:

o-Methylsulfon-ω-diazo-acetophenon (90417-64-4) → 2-methylsulphonylbenzaldehyde (5395-89-1)

Guidance literature:

Multi-step reaction with 3 steps

1: KOAc

2: LiAlH₄ / diethyl ether

3: Pb(OAc)4 / benzene

With lead(IV) acetate; lithium aluminium tetrahydride; potassium acetate; In diethyl ether; benzene;

upstream raw materials:

1-methyl-2-(methylsulfonyl)benzene

2-(methylsulfanyl)benzaldehyde

o-Methylsulfon-phenylaethylenglykol

methyl o-tolyl sulfide

Refernces

• 1、 -. "BENZENESULFONAMIDE DERIVATIVES". . . Retrieved 2008/06/13.