dimethyl 2-[2-(tert-butyldimethylsilyloxy)ethyl]-2-[4-(2,2-diphenylcyclopropyl)-4-oxobut-2-ynyl]malonate

Base Information

• Chemical Name: dimethyl 2-[2-(tert-butyldimethylsilyloxy)ethyl]-2-[4-(2,2-diphenylcyclopropyl)-4-oxobut-2-ynyl]malonate
• CAS No.: 1449327-63-2
• Molecular Formula: C₃₂H₄₀O₆Si
• Molecular Weight: 548.751

Synonyms:dimethyl 2-[2-(tert-butyldimethylsilyloxy)ethyl]-2-[4-(2,2-diphenylcyclopropyl)-4-oxobut-2-ynyl]malonate

Chemical Property of dimethyl 2-[2-(tert-butyldimethylsilyloxy)ethyl]-2-[4-(2,2-diphenylcyclopropyl)-4-oxobut-2-ynyl]malonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of dimethyl 2-[2-(tert-butyldimethylsilyloxy)ethyl]-2-[4-(2,2-diphenylcyclopropyl)-4-oxobut-2-ynyl]malonate

There total 3 articles about dimethyl 2-[2-(tert-butyldimethylsilyloxy)ethyl]-2-[4-(2,2-diphenylcyclopropyl)-4-oxobut-2-ynyl]malonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C32H42O6Si → dimethyl 2-[2-(tert-butyldimethylsilyloxy)ethyl]-2-[4-(2,2-diphenylcyclopropyl)-4-oxobut-2-ynyl]malonate (1449327-63-2)

Guidance literature:

With manganese(IV) oxide; In dichloromethane; at 20 ℃; for 24h;

DOI:10.1016/j.tet.2013.05.056

Reference yield:

2,2-diphenylcyclopropylmethanol (37555-48-9) → dimethyl 2-[2-(tert-butyldimethylsilyloxy)ethyl]-2-[4-(2,2-diphenylcyclopropyl)-4-oxobut-2-ynyl]malonate (1449327-63-2)

Guidance literature:

Multi-step reaction with 3 steps

1.1: pyridinium chlorochromate / dichloromethane / 20 °C

2.1: n-butyllithium / hexane; tetrahydrofuran / -78 °C

2.2: 0.5 h / -78 °C

3.1: manganese(IV) oxide / dichloromethane / 24 h / 20 °C

With manganese(IV) oxide; n-butyllithium; pyridinium chlorochromate; In tetrahydrofuran; hexane; dichloromethane;

DOI:10.1016/j.tet.2013.05.056

Reference yield:

2,2-diphenylcyclopropanecarbaldehyde (59591-01-4) → dimethyl 2-[2-(tert-butyldimethylsilyloxy)ethyl]-2-[4-(2,2-diphenylcyclopropyl)-4-oxobut-2-ynyl]malonate (1449327-63-2)

Guidance literature:

Multi-step reaction with 2 steps

1.1: n-butyllithium / hexane; tetrahydrofuran / -78 °C

1.2: 0.5 h / -78 °C

2.1: manganese(IV) oxide / dichloromethane / 24 h / 20 °C

With manganese(IV) oxide; n-butyllithium; In tetrahydrofuran; hexane; dichloromethane;

DOI:10.1016/j.tet.2013.05.056

upstream raw materials:

2,2-diphenylcyclopropanecarbaldehyde

2,2-diphenylcyclopropylmethanol

Downstream raw materials:

hexacarbonyl-μ{η⁴-9.9-dimethoxycarbonyl-2,2-diphenyl-1,6-dioxaspiro[4.7]dodec-11-yne}dicobalt

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1449327-63-2 dimethyl 2-[2-(tert-butyldimethylsilyloxy)ethyl]-2-[4-(2,2-diphenylcyclopropyl)-4-oxobut-2-ynyl]malonate

Send

Send

Metric Ton KG G Pound L ML

Send

Send