2-{4-[3-(2-chloropyridin-4-ylmethyl)-4,4-dimethyl-2,5-dioxo-imidazolidin-1-yl]-phenyl}-2-methylpropionic acid methyl ester

Base Information

Chemical Name:2-{4-[3-(2-chloropyridin-4-ylmethyl)-4,4-dimethyl-2,5-dioxo-imidazolidin-1-yl]-phenyl}-2-methylpropionic acid methyl ester
CAS No.:945104-50-7
Molecular Formula:C₂₂H₂₄ClN₃O₄
Molecular Weight:429.903
Hs Code.:

Synonyms:2-{4-[3-(2-chloropyridin-4-ylmethyl)-4,4-dimethyl-2,5-dioxo-imidazolidin-1-yl]-phenyl}-2-methylpropionic acid methyl ester

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Chemical Property of 2-{4-[3-(2-chloropyridin-4-ylmethyl)-4,4-dimethyl-2,5-dioxo-imidazolidin-1-yl]-phenyl}-2-methylpropionic acid methyl ester

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Technology Process of 2-{4-[3-(2-chloropyridin-4-ylmethyl)-4,4-dimethyl-2,5-dioxo-imidazolidin-1-yl]-phenyl}-2-methylpropionic acid methyl ester

There total 1 articles about 2-{4-[3-(2-chloropyridin-4-ylmethyl)-4,4-dimethyl-2,5-dioxo-imidazolidin-1-yl]-phenyl}-2-methylpropionic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 101990-73-2
2-chloro-pyridin-4-ylmethyl chloride

: 945104-51-8
methyl 2-[4-(4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)phenyl]-2-methylpropanoate

: 945104-50-7
2-{4-[3-(2-chloropyridin-4-ylmethyl)-4,4-dimethyl-2,5-dioxo-imidazolidin-1-yl]-phenyl}-2-methylpropionic acid methyl ester

Guidance literature:: methyl 2-[4-(4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)phenyl]-2-methylpropanoate; With sodium hydride; In N,N-dimethyl-formamide; at 20 ℃; for 0.333333h;

2-chloro-pyridin-4-ylmethyl chloride; In N,N-dimethyl-formamide; at 60 ℃; for 5h;

Reference yield:

: 462-08-8
pyridin-3-ylamine

: 945104-50-7
2-{4-[3-(2-chloropyridin-4-ylmethyl)-4,4-dimethyl-2,5-dioxo-imidazolidin-1-yl]-phenyl}-2-methylpropionic acid methyl ester

: 945104-49-4
methyl 2-[4-(4,4-dimethyl-2,5-dioxo-3-{[2-(pyridin-3-ylamino)pyridin-4-yl]methyl}imidazolidin-1-yl)phenyl]-2-methylpropanoate

Guidance literature:: With caesium carbonate; palladium diacetate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In 1,4-dioxane; for 4h; Heating / reflux;