Technology Process of Methyl 4-(chlorosulfonyl)-5-methylthiophene-3-carboxylate
There total 5 articles about Methyl 4-(chlorosulfonyl)-5-methylthiophene-3-carboxylate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
C7H7O2S2(1-)*Li(1+);
With
hydrogenchloride; water;
In
tetrahydrofuran;
for 3h;
pH=6;
Cooling with ice;
With
chlorine;
In
tetrahydrofuran;
Concentration;
pH-value;
- Guidance literature:
-
4-methoxycarbonyl-2-methylthiophene-3-amine hydrochloride;
With
sodium nitrite;
In
water;
at 5 ℃;
for 0.05h;
Flow reactor;
With
sulfur dioxide; trimethyldodecylammonium chloride; copper dichloride;
In
water; 1,2-dichloro-ethane;
at 35 ℃;
for 0.0333333h;
Temperature;
Reagent/catalyst;
Flow reactor;
- Guidance literature:
-
With
water; chlorine;
at 0 - 5 ℃;