Technology Process of Cyclohexanone, 2-(hydroxymethyl)-3-(methoxymethoxy)-2-methyl-, (2R,3S)- (9CI)
There total 2 articles about Cyclohexanone, 2-(hydroxymethyl)-3-(methoxymethoxy)-2-methyl-, (2R,3S)- (9CI) which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 95 percent / DIPEA; NaI / CH2Cl2 / 48 h / Heating
2: 100 percent / H2 / Pd/C / methanol / 10 h
With
hydrogen; N-ethyl-N,N-diisopropylamine; sodium iodide;
palladium on activated charcoal;
In
methanol; dichloromethane;
DOI:10.1016/j.tetlet.2004.09.143
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 74 percent / imidazole / CH2Cl2 / 1 h
2: 96 percent / NaI / acetone / 10 h / Heating
3: 64 percent / t-BuLi / 0.08 h / -78 °C
4: aq. H2O2; KHCO3; KF / tetrahydrofuran; methanol / 10 h
5: 100 percent / DMAP / CH2Cl2
With
1H-imidazole; dmap; potassium fluoride; dihydrogen peroxide; tert.-butyl lithium; potassium hydrogencarbonate; sodium iodide;
In
tetrahydrofuran; methanol; dichloromethane; acetone;
4: Tamao oxidation;
DOI:10.1016/j.tetlet.2004.09.143
