3-[(Acetylmethylamino)methyl]benzoic acid

Base Information

Chemical Name:3-[(Acetylmethylamino)methyl]benzoic acid
CAS No.:446263-92-9
Molecular Formula:C₁₁H₁₃NO₃
Molecular Weight:207.229
Hs Code.:
DSSTox Substance ID:DTXSID301269402

Synonyms:446263-92-9;DTXSID301269402;3-[(Acetylmethylamino)methyl]benzoic acid;3-[(N-methylacetamido)methyl]benzoic acid;EN300-9425880

Suppliers and Price of 3-[(Acetylmethylamino)methyl]benzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-[(Acetylmethylamino)methyl]benzoic acid

Chemical Property:

XLogP3:0.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:207.08954328
Heavy Atom Count:15
Complexity:252

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(=O)N(C)CC1=CC(=CC=C1)C(=O)O

Technology Process of 3-[(Acetylmethylamino)methyl]benzoic acid

There total 2 articles about 3-[(Acetylmethylamino)methyl]benzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 31719-77-4
3-chloromethylbenzoic acid

: 446263-92-9
3-[(N-acetyl-N-methylamino)methyl]benzoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: methanol / 16 h / 50 °C

2: 0.65 g / Et₃N / CHCl₃ / 3 h

With triethylamine; In methanol; chloroform;
DOI:10.1021/jm020050+

Reference yield:

: 108-24-7
acetic anhydride

: 446263-91-8
N-methyl-3-aminomethyl-benzoic acid

: 446263-92-9
3-[(N-acetyl-N-methylamino)methyl]benzoic acid

Guidance literature:: With triethylamine; In chloroform; for 3h;
DOI:10.1021/jm020050+

Reference yield: 86.0%

: 3514-15-6
1-methyl-2-(methylaminomethyl)-1H-indole

: 446263-92-9
3-[(N-acetyl-N-methylamino)methyl]benzoic acid

: 3-[(acetyl-methyl-amino)-methyl]-N-methyl-N-(1-methyl-1H-indol-2-ylmethyl)-benzamide

Guidance literature:: With benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; triethylamine; In dichloromethane; N,N-dimethyl-formamide; at 20 ℃; for 16h;
DOI:10.1021/jm020050+