(5S)-[5-(2,2-dimethyl-1,1-diphenyl-1-silapropoxy)cyclopent-1-enyl](phenylmethoxy)methane

Base Information

• Chemical Name: (5S)-[5-(2,2-dimethyl-1,1-diphenyl-1-silapropoxy)cyclopent-1-enyl](phenylmethoxy)methane
• CAS No.: 325464-38-8
• Molecular Formula: C₂₉H₃₄O₂Si
• Molecular Weight: 442.673
• Mol file: 325464-38-8.mol

Synonyms:(5S)-[5-(2,2-dimethyl-1,1-diphenyl-1-silapropoxy)cyclopent-1-enyl](phenylmethoxy)methane

Chemical Property of (5S)-[5-(2,2-dimethyl-1,1-diphenyl-1-silapropoxy)cyclopent-1-enyl](phenylmethoxy)methane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (5S)-[5-(2,2-dimethyl-1,1-diphenyl-1-silapropoxy)cyclopent-1-enyl](phenylmethoxy)methane

There total 4 articles about (5S)-[5-(2,2-dimethyl-1,1-diphenyl-1-silapropoxy)cyclopent-1-enyl](phenylmethoxy)methane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

((1S,2R)-2-Benzyloxymethyl-cyclopent-3-enyloxy)-tert-butyl-diphenyl-silane (191480-67-8) → (5S)-[5-(2,2-dimethyl-1,1-diphenyl-1-silapropoxy)cyclopent-1-enyl](phenylmethoxy)methane (325464-38-8)

Guidance literature:

Multi-step reaction with 5 steps

1: dimethylsulfoxide

2: 73 percent / NaIO₄ / methanol; H₂O

3: SO₃; pyridine

4: LiAlH₄ / tetrahydrofuran

With pyridine; sodium periodate; lithium aluminium tetrahydride; sulfur trioxide; In tetrahydrofuran; methanol; water; dimethyl sulfoxide;

DOI:10.1081/NCN-100002319

Reference yield:

(1S,2S,3R,4S)-4-(2,2-dimethyl-1,1-diphenyl-1-silapropoxy)-3-[(phenylmethoxy)methyl]-2-(phenylselenamethyl)cyclopentan-1-ol (325464-35-5) → (5S)-[5-(2,2-dimethyl-1,1-diphenyl-1-silapropoxy)cyclopent-1-enyl](phenylmethoxy)methane (325464-38-8)

Guidance literature:

Multi-step reaction with 3 steps

1: 73 percent / NaIO₄ / methanol; H₂O

2: SO₃; pyridine

3: LiAlH₄ / tetrahydrofuran

With pyridine; sodium periodate; lithium aluminium tetrahydride; sulfur trioxide; In tetrahydrofuran; methanol; water;

DOI:10.1081/NCN-100002319

Reference yield:

Trifluoro-acetic acid (1S,2S,3R,4S)-3-benzyloxymethyl-4-(tert-butyl-diphenyl-silanyloxy)-2-phenylselanyl-cyclopentyl ester (325464-33-3) → (5S)-[5-(2,2-dimethyl-1,1-diphenyl-1-silapropoxy)cyclopent-1-enyl](phenylmethoxy)methane (325464-38-8)

Guidance literature:

Multi-step reaction with 4 steps

1: 73 percent / NaIO₄ / methanol; H₂O

2: SO₃; pyridine

3: LiAlH₄ / tetrahydrofuran

With pyridine; sodium periodate; lithium aluminium tetrahydride; sulfur trioxide; In tetrahydrofuran; methanol; water;

DOI:10.1081/NCN-100002319

upstream raw materials:

((1S,2R)-2-Benzyloxymethyl-cyclopent-3-enyloxy)-tert-butyl-diphenyl-silane

(1S,2S,3R,4S)-4-(2,2-dimethyl-1,1-diphenyl-1-silapropoxy)-3-[(phenylmethoxy)methyl]-2-(phenylselenamethyl)cyclopentan-1-ol

Trifluoro-acetic acid (1S,2S,3R,4S)-3-benzyloxymethyl-4-(tert-butyl-diphenyl-silanyloxy)-2-phenylselanyl-cyclopentyl ester

Downstream raw materials:

(1S)-2-[(phenylmethoxy)methyl]cyclopent-2-en-1-ol

(1R,2S,5S)-1-{[bis(4-methoxyphenyl)phenylmethoxy]methyl}bicyclo[3.1.0]hexan-2-ol

(1R,2S,5S)-1-[(phenylmethoxy)methyl]bicyclo[3.1.0]hexan-2-ol