3-Biphenyl-4-yl-N-(2-chloro-benzyl)-N-hydroxy-3-phenyl-thiopropionamide

Base Information

Chemical Name:3-Biphenyl-4-yl-N-(2-chloro-benzyl)-N-hydroxy-3-phenyl-thiopropionamide
CAS No.:139025-02-8
Molecular Formula:C₂₈H₂₄ClNOS
Molecular Weight:458.024
Hs Code.:

Synonyms:3-Biphenyl-4-yl-N-(2-chloro-benzyl)-N-hydroxy-3-phenyl-thiopropionamide

Suppliers and Price of 3-Biphenyl-4-yl-N-(2-chloro-benzyl)-N-hydroxy-3-phenyl-thiopropionamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-Biphenyl-4-yl-N-(2-chloro-benzyl)-N-hydroxy-3-phenyl-thiopropionamide

Chemical Property:

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Technology Process of 3-Biphenyl-4-yl-N-(2-chloro-benzyl)-N-hydroxy-3-phenyl-thiopropionamide

There total 2 articles about 3-Biphenyl-4-yl-N-(2-chloro-benzyl)-N-hydroxy-3-phenyl-thiopropionamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 92-52-4,1594-86-1
biphenyl

: 139025-11-9
2-(o-Chlorobenzyl)-5-phenylisoxazolidine-3-thione

: 139025-02-8
3-Biphenyl-4-yl-N-(2-chloro-benzyl)-N-hydroxy-3-phenyl-thiopropionamide

Guidance literature:: With aluminium trichloride; In dichloromethane; for 2.5h; Ambient temperature;
DOI:10.1055/s-1991-26615

Reference yield:

: 139025-09-5
2-(o-Chlorobenzyl)-5-phenylisoxazolidine-3-thione

: 139025-02-8
3-Biphenyl-4-yl-N-(2-chloro-benzyl)-N-hydroxy-3-phenyl-thiopropionamide

Guidance literature:: Multi-step reaction with 2 steps

1: 85 percent / phosphorus pentasulfide / benzene / 1 h / Heating

2: 74 percent / aluminum chloride / CH₂Cl₂ / 2.5 h / Ambient temperature

With diphosphorus pentasulfide; aluminium trichloride; In dichloromethane; benzene;
DOI:10.1055/s-1991-26615