2-(diethoxy-phosphorylmethyl)-5-nitro-benzenesulfonic acid 2,2-dimethyl-propyl ester

Base Information

• Chemical Name: 2-(diethoxy-phosphorylmethyl)-5-nitro-benzenesulfonic acid 2,2-dimethyl-propyl ester
• CAS No.: 299183-43-0
• Molecular Formula: C₁₆H₂₆NO₈PS
• Molecular Weight: 423.424

Synonyms:2-(diethoxy-phosphorylmethyl)-5-nitro-benzenesulfonic acid 2,2-dimethyl-propyl ester

Chemical Property of 2-(diethoxy-phosphorylmethyl)-5-nitro-benzenesulfonic acid 2,2-dimethyl-propyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(diethoxy-phosphorylmethyl)-5-nitro-benzenesulfonic acid 2,2-dimethyl-propyl ester

There total 4 articles about 2-(diethoxy-phosphorylmethyl)-5-nitro-benzenesulfonic acid 2,2-dimethyl-propyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

2-bromomethyl-5-nitro-benzenesulfonic acid, 2,2-dimethylpropyl ester (299183-35-0) + triethyl phosphite (122-52-1) → 2-(diethoxy-phosphorylmethyl)-5-nitro-benzenesulfonic acid 2,2-dimethyl-propyl ester (299183-43-0)

Guidance literature:

In o-xylene; at 100 ℃;

DOI:10.1016/S0968-0896(01)00324-8

Reference yield:

2,2-dimethyl-propanol-1 (75-84-3) → 2-(diethoxy-phosphorylmethyl)-5-nitro-benzenesulfonic acid 2,2-dimethyl-propyl ester (299183-43-0)

Guidance literature:

Multi-step reaction with 3 steps

1: 55 percent / pyridine / dioxane / Heating

2: 55 percent / NBS; (PhCO₂)2 / CCl₄ / Heating

3: 60 percent / o-xylene / 100 °C

With pyridine; N-Bromosuccinimide; dibenzoyl peroxide; In 1,4-dioxane; tetrachloromethane; o-xylene; 3: Arbuzov rearrangement;

DOI:10.1016/S0968-0896(01)00324-8

Reference yield:

2-methyl-5-nitrobenzene-1-sulfonyl chloride (121-02-8) → 2-(diethoxy-phosphorylmethyl)-5-nitro-benzenesulfonic acid 2,2-dimethyl-propyl ester (299183-43-0)

Guidance literature:

Multi-step reaction with 3 steps

1: 55 percent / pyridine / dioxane / Heating

2: 55 percent / NBS; (PhCO₂)2 / CCl₄ / Heating

3: 60 percent / o-xylene / 100 °C

With pyridine; N-Bromosuccinimide; dibenzoyl peroxide; In 1,4-dioxane; tetrachloromethane; o-xylene; 3: Arbuzov rearrangement;

DOI:10.1016/S0968-0896(01)00324-8

upstream raw materials:

2-bromomethyl-5-nitro-benzenesulfonic acid, 2,2-dimethylpropyl ester

triethyl phosphite

2,2-dimethyl-propanol-1

2-methyl-5-nitrobenzene-1-sulfonyl chloride

Downstream raw materials:

5-[4-Methylsulfanyl-3-(morpholine-4-sulfonyl)-benzoylamino]-2-((E)-2-{4-[4-methylsulfanyl-3-(morpholine-4-sulfonyl)-benzoylamino]-phenyl}-vinyl)-benzenesulfonic acid 2,2-dimethyl-propyl ester

5-Amino-2-[(E)-2-(4-amino-phenyl)-vinyl]-benzenesulfonic acid 2,2-dimethyl-propyl ester

5-Nitro-2-[2-(4-nitro-phenyl)-vinyl]-benzenesulfonic acid 2,2-dimethylpropyl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 299183-43-0 2-(diethoxy-phosphorylmethyl)-5-nitro-benzenesulfonic acid 2,2-dimethyl-propyl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send