5'-O-(4,4'-dimethoxytrityl)-2'-O-[[[4-(dimethylamino)benzyl]oxy]methyl]uridine

Base Information

Chemical Name:5'-O-(4,4'-dimethoxytrityl)-2'-O-[[[4-(dimethylamino)benzyl]oxy]methyl]uridine
CAS No.:934758-41-5
Molecular Formula:C₄₀H₄₃N₃O₉
Molecular Weight:709.796
Hs Code.:

Synonyms:5'-O-(4,4'-dimethoxytrityl)-2'-O-[[[4-(dimethylamino)benzyl]oxy]methyl]uridine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5'-O-(4,4'-dimethoxytrityl)-2'-O-[[[4-(dimethylamino)benzyl]oxy]methyl]uridine

Chemical Property:

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Technology Process of 5'-O-(4,4'-dimethoxytrityl)-2'-O-[[[4-(dimethylamino)benzyl]oxy]methyl]uridine

There total 1 articles about 5'-O-(4,4'-dimethoxytrityl)-2'-O-[[[4-(dimethylamino)benzyl]oxy]methyl]uridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 929896-94-6
2'-O-[[[4-(dimethylamino)benzyl]oxy]methyl]uridine

: 40615-36-9
4,4'-dimethoxytrityl chloride

: 934758-41-5
5'-O-(4,4'-dimethoxytrityl)-2'-O-[[[4-(dimethylamino)benzyl]oxy]methyl]uridine

Guidance literature:: With pyridine; at 25 ℃; for 2h;
DOI:10.1021/ol0629824

Reference yield:

: 934758-41-5
5'-O-(4,4'-dimethoxytrityl)-2'-O-[[[4-(dimethylamino)benzyl]oxy]methyl]uridine

: 124482-92-4,89992-70-1
2-cyanoethyl-N,N-(diisopropylamino)chlorophosphine

: 929896-95-7
C₄₉H₆₀N₅O₁₀P

Guidance literature:: With triethylamine; In dichloromethane; at 25 ℃; for 2h;
DOI:10.1021/ol0629824

Reference yield:

: 934758-41-5
5'-O-(4,4'-dimethoxytrityl)-2'-O-[[[4-(dimethylamino)benzyl]oxy]methyl]uridine

: C₂₉H₃₈N₅O₁₄P

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / CH₂Cl₂ / 2 h / 25 °C

With triethylamine; In dichloromethane;
DOI:10.1021/ol0629824