(4R)-4-(3,4-DiMethoxyphenyl)-4-(2-propen-1-yl)-2-cyclohexen-1-one

Base Information

Chemical Name:(4R)-4-(3,4-DiMethoxyphenyl)-4-(2-propen-1-yl)-2-cyclohexen-1-one
CAS No.:866394-49-2
Molecular Formula:C₁₇H₂₀O₃
Molecular Weight:272.344
Hs Code.:
Mol file:866394-49-2.mol

Synonyms:(R)-1-allyl-3',4'-dimethoxy-2,3-dihydro-[1,1'-biphenyl]-4(1H)-one

Suppliers and Price of (4R)-4-(3,4-DiMethoxyphenyl)-4-(2-propen-1-yl)-2-cyclohexen-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(4R)-4-(3,4-Dimethoxyphenyl)-4-(2-propen-1-yl)-2-cyclohexen-1-one
2.5mg
$ 165.00

Medical Isotopes, Inc.
(4R)-4-(3,4-Dimethoxyphenyl)-4-(2-propen-1-yl)-2-cyclohexen-1-one
25 mg
$ 2200.00

Total 2 raw suppliers

Chemical Property of (4R)-4-(3,4-DiMethoxyphenyl)-4-(2-propen-1-yl)-2-cyclohexen-1-one

Chemical Property:

Solubility.:Chloroform, Ethyl Acetate

Purity/Quality:

98% ^*data from raw suppliers

(4R)-4-(3,4-Dimethoxyphenyl)-4-(2-propen-1-yl)-2-cyclohexen-1-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses (4R)-4-(3,4-Dimethoxyphenyl)-4-(2-propen-1-yl)-2-cyclohexen-1-one is an intermediate in the synthesis of Mesembrine (M338950), a serotonin-uptake inhibitor which occurs naturally as the (-)-form.

Technology Process of (4R)-4-(3,4-DiMethoxyphenyl)-4-(2-propen-1-yl)-2-cyclohexen-1-one

There total 9 articles about (4R)-4-(3,4-DiMethoxyphenyl)-4-(2-propen-1-yl)-2-cyclohexen-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 866394-48-1
(7R,8S)-8-Allyl-8-(3,4-dimethoxy-phenyl)-1,4-dioxa-spiro[4.5]decan-7-ol

: 866394-49-2
(R)-1-allyl-3',4'-dimethoxy-2,3-dihydro-[1,1'-biphenyl]-4(1H)-one

Guidance literature:: With hydrogenchloride; In tetrahydrofuran; water;
DOI:10.1021/jo0511039

Reference yield: 82.0%

: (-)-(S)-2-allyl-2-(3,4-dimethoxyphenyl)-5-oxohexanal

: 866394-49-2
(R)-1-allyl-3',4'-dimethoxy-2,3-dihydro-[1,1'-biphenyl]-4(1H)-one

Guidance literature:: With toluene-4-sulfonic acid; In benzene; for 1.5h; Heating;
DOI:10.1021/jo701833v

Reference yield: 70.0%

: (S)-6-allyl-3-ethoxy-6-(3',4'-dimethoxy-phenyl)cyclohex-2-en-1-one

: 866394-49-2
(R)-1-allyl-3',4'-dimethoxy-2,3-dihydro-[1,1'-biphenyl]-4(1H)-one

Guidance literature:: (S)-6-allyl-3-ethoxy-6-(3',4'-dimethoxy-phenyl)cyclohex-2-en-1-one; With diisobutylaluminium hydride; In toluene; at -78 - -20 ℃; for 2.33333h; Inert atmosphere;

With hydrogenchloride; In methanol; water; at -78 - 20 ℃; for 12h; Inert atmosphere;
DOI:10.1021/acs.orglett.0c04125