Technology Process of 2-{[6-methoxy-1-(phenylsulfonyl)-1H-indol-5-yl]oxy}ethanamine
There total 5 articles about 2-{[6-methoxy-1-(phenylsulfonyl)-1H-indol-5-yl]oxy}ethanamine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
trifluoroacetic acid;
In
dichloromethane;
at 20 ℃;
for 0.5h;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: hydrogenchloride; cyclohexene / palladium 10% on activated carbon / ethanol; water / 0.08 h / 150 °C / Microwave irradiation
2: diamide; triphenylphosphine / dichloromethane / 0.33 h / 150 °C / Microwave irradiation
3: trifluoroacetic acid / dichloromethane / 0.5 h / 20 °C
With
hydrogenchloride; diamide; triphenylphosphine; trifluoroacetic acid; cyclohexene;
palladium 10% on activated carbon;
In
ethanol; dichloromethane; water;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate / dichloromethane; water / 20 °C
2: hydrogenchloride; cyclohexene / palladium 10% on activated carbon / ethanol; water / 0.08 h / 150 °C / Microwave irradiation
3: diamide; triphenylphosphine / dichloromethane / 0.33 h / 150 °C / Microwave irradiation
4: trifluoroacetic acid / dichloromethane / 0.5 h / 20 °C
With
hydrogenchloride; sodium hydroxide; diamide; tetra(n-butyl)ammonium hydrogensulfate; triphenylphosphine; trifluoroacetic acid; cyclohexene;
palladium 10% on activated carbon;
In
ethanol; dichloromethane; water;
