methyl 2-(7-bromo-4-methoxy-1H-pyrrolo[2,3-c]pyridin-3-yl)-2-oxoacetate

Base Information

Chemical Name:methyl 2-(7-bromo-4-methoxy-1H-pyrrolo[2,3-c]pyridin-3-yl)-2-oxoacetate
CAS No.:954215-11-3
Molecular Formula:C₁₁H₉BrN₂O₄
Molecular Weight:313.107
Hs Code.:
Mol file:954215-11-3.mol

Synonyms:methyl 2-(7-bromo-4-methoxy-6-azaindol-3-yl)-2-oxoacetate

Suppliers and Price of methyl 2-(7-bromo-4-methoxy-1H-pyrrolo[2,3-c]pyridin-3-yl)-2-oxoacetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

TRC
Methyl2-(7-Bromo-4-methoxy-1H-pyrrolo[2,3-c]pyridin-3-yl)-2-oxoacetate
10mg
$ 1320.00

Total 7 raw suppliers

Chemical Property of methyl 2-(7-bromo-4-methoxy-1H-pyrrolo[2,3-c]pyridin-3-yl)-2-oxoacetate

Chemical Property:

Boiling Point:500.0±40.0 °C(Predicted)
PKA:10.76±0.40(Predicted)
Density:1.676±0.06 g/cm3(Predicted)

Purity/Quality:

99% ^*data from raw suppliers

Methyl2-(7-Bromo-4-methoxy-1H-pyrrolo[2,3-c]pyridin-3-yl)-2-oxoacetate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses Methyl 2-(7-Bromo-4-methoxy-1H-pyrrolo[2,3-c]pyridin-3-yl)-2-oxoacetate is a Fostemsavir (864953-29-7) intermediate and an antiviral agent.

Technology Process of methyl 2-(7-bromo-4-methoxy-1H-pyrrolo[2,3-c]pyridin-3-yl)-2-oxoacetate

There total 3 articles about methyl 2-(7-bromo-4-methoxy-1H-pyrrolo[2,3-c]pyridin-3-yl)-2-oxoacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 5781-53-3
monomethyl oxalyl chloride

: 619331-35-0
7-bromo-4-methoxy-6-azaindole

: 954215-11-3
methyl 2-(7-bromo-4-methoxy-6-azaindol-3-yl)-2-oxoacetate

Guidance literature:: monomethyl oxalyl chloride; 7-bromo-4-methoxy-6-azaindole; aluminum (III) chloride; In nitromethane; dichloromethane; at 20 ℃; for 1h;

With ammonia; water; In nitromethane; dichloromethane;

Reference yield:

: 5781-53-3
monomethyl oxalyl chloride

: 7-bromo-4-methoxy-1H-pyrrolo[2,3-c]pyridine hydrochloride

: 954215-11-3
methyl 2-(7-bromo-4-methoxy-6-azaindol-3-yl)-2-oxoacetate

: 954215-12-4
2-(7-bromo-4-methoxy-1H-pyrrolo[2,3-c]pyridin-3-yl)-2-oxoacetic acid

Guidance literature:: With aluminum (III) chloride; tetra(n-butyl)ammonium hydrogensulfate; In dichloromethane; at 0 - 15 ℃; Reagent/catalyst; Inert atmosphere; Industrial scale;
DOI:10.1021/acs.oprd.7b00133

Reference yield:

: 5781-53-3
monomethyl oxalyl chloride

: 7-bromo-4-methoxy-1H-pyrrolo[2,3-c]pyridine hydrochloride

: 954215-11-3
methyl 2-(7-bromo-4-methoxy-6-azaindol-3-yl)-2-oxoacetate

: 954215-12-4
2-(7-bromo-4-methoxy-1H-pyrrolo[2,3-c]pyridin-3-yl)-2-oxoacetic acid

: C₁₀H₇BrN₂O₄

Guidance literature:: With aluminum (III) chloride; tetra(n-butyl)ammonium hydrogensulfate; In dichloromethane; at 20 ℃; Inert atmosphere;
DOI:10.1021/acs.oprd.7b00133