(-)-6-(4-aminophenyl)-4,5-dihydro-5-methyl-3-(2H)-pyridazinone di-p-anisoyl-D-tartrate

Base Information

• Chemical Name: (-)-6-(4-aminophenyl)-4,5-dihydro-5-methyl-3-(2H)-pyridazinone di-p-anisoyl-D-tartrate
• CAS No.: 1260774-44-4
• Molecular Formula: C₁₁H₁₃N₃O*C₂₀H₁₈O₁₀
• Molecular Weight: 621.601
• Mol file: 1260774-44-4.mol

Synonyms:(-)-6-(4-aminophenyl)-4,5-dihydro-5-methyl-3-(2H)-pyridazinone di-p-anisoyl-D-tartrate

Chemical Property of (-)-6-(4-aminophenyl)-4,5-dihydro-5-methyl-3-(2H)-pyridazinone di-p-anisoyl-D-tartrate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (-)-6-(4-aminophenyl)-4,5-dihydro-5-methyl-3-(2H)-pyridazinone di-p-anisoyl-D-tartrate

There total 1 articles about (-)-6-(4-aminophenyl)-4,5-dihydro-5-methyl-3-(2H)-pyridazinone di-p-anisoyl-D-tartrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

O,O′-di-p-anisoyl-D-tartaric acid (50583-51-2,191605-10-4) + 6-(4-aminophenyl)-4,5-dihydro-5-methyl-3(2H)-pyridazinone (36725-28-7) → (-)-6-(4-aminophenyl)-4,5-dihydro-5-methyl-3-(2H)-pyridazinone di-p-anisoyl-D-tartrate (1260774-44-4) + (5S)-6-(4-aminophenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-one (101328-84-1)

Guidance literature:

In ethanol; water; at 15 - 65 ℃; for 1.5h;

Reference yield:

(-)-6-(4-aminophenyl)-4,5-dihydro-5-methyl-3-(2H)-pyridazinone di-p-anisoyl-D-tartrate (1260774-44-4) → levosimendan (141505-33-1,144238-75-5)

Guidance literature:

Multi-step reaction with 2 steps

1.1: ammonia / water / 0.5 h / 25 - 30 °C / pH 8 - 9

2.1: hydrogenchloride; sodium nitrite / water / 0.17 h

2.2: 1 h / 20 °C

2.3: pH 6

With hydrogenchloride; ammonia; sodium nitrite; In water;

Reference yield:

(-)-6-(4-aminophenyl)-4,5-dihydro-5-methyl-3-(2H)-pyridazinone di-p-anisoyl-D-tartrate (1260774-44-4) → OR-1855 (36725-28-7,101328-84-1,101328-85-2,107295-33-0)

Guidance literature:

With ammonia; In water; at 25 - 30 ℃; for 0.5h; pH=8 - 9;

upstream raw materials:

O,O′-di-p-anisoyl-D-tartaric acid

6-(4-aminophenyl)-4,5-dihydro-5-methyl-3(2H)-pyridazinone

Downstream raw materials:

levosimendan

OR-1855

Refernces