3-PROPOXY-AZETIDINE HYDROCHLORIDE

Base Information

• Chemical Name: 3-PROPOXY-AZETIDINE HYDROCHLORIDE
• CAS No.: 897019-55-5
• Molecular Formula: C6H13 N O . Cl H
• Molecular Weight: 151.636
• Hs Code.: 2933998090
• Mol file: 897019-55-5.mol

Synonyms:Azetidine,3-propoxy-, hydrochloride (9CI)

Chemical Property of 3-PROPOXY-AZETIDINE HYDROCHLORIDE

Chemical Property:

• PSA: 21.26000
• LogP: 1.51560

Purity/Quality:

98%min ^*data from raw suppliers

3-Propoxy-azetidineHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-PROPOXY-AZETIDINE HYDROCHLORIDE

There total 1 articles about 3-PROPOXY-AZETIDINE HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-diphenylmethyl-3-propoxy-azetidine (897019-47-5) → 3-propoxyazetidine hydrochloride (897019-55-5)

Guidance literature:

1-diphenylmethyl-3-propoxy-azetidine; With carbonochloridic acid 1-chloro-ethyl ester; In 1,2-dichloro-ethane; at 70 ℃; for 1.5h;

With methanol; In 1,2-dichloro-ethane; at 20 - 70 ℃; for 1.5h;

Reference yield: 92.0%

phenyl-3-(4-chlorophenyl)-N-cyano-4-(2-oxopyrrolidin-1-yl)-4,5-dihydro-1H-pyrazol-1-carboximidoate (832753-56-7) + 3-propoxyazetidine hydrochloride (897019-55-5) → ((3-(4-chlorophenyl)-4-(2-oxopyrrolidin-1-yl)-4,5-dihydro-1H-pyrazol-1-yl)(3-propoxyazetidin-1-yl)methylene)-cyanamide

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 16h;

Reference yield: 22.0%

3-propoxyazetidine hydrochloride (897019-55-5) + (S)-3-(4-(4-(bromomethyl)benzyloxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione (1323408-85-0) → (S)-3-(1-oxo-4-((4-((3-propoxyazetidin-1-yl)methyl)benzyl)oxy)isoindolin-2-yl)piperidine-2,6-dione hydrochloride

Guidance literature:

3-propoxyazetidine hydrochloride; (S)-3-(4-(4-(bromomethyl)benzyloxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione; With N-ethyl-N,N-diisopropylamine; In acetonitrile; at 20 - 50 ℃; for 3.5h;

With hydrogenchloride; In water;

upstream raw materials:

1-diphenylmethyl-3-propoxy-azetidine

Refernces