11-amino-N-(3-fluoro-4-morpholinophenyl)-2'-O-benzoyl-11-deoxy-3-O-descladinosyl-3-oxoclarithromycin 11,12-carbamate

Base Information

Chemical Name:11-amino-N-(3-fluoro-4-morpholinophenyl)-2'-O-benzoyl-11-deoxy-3-O-descladinosyl-3-oxoclarithromycin 11,12-carbamate
CAS No.:898833-60-8
Molecular Formula:C₄₈H₆₆FN₃O₁₂
Molecular Weight:896.063
Hs Code.:

Synonyms:11-amino-N-(3-fluoro-4-morpholinophenyl)-2'-O-benzoyl-11-deoxy-3-O-descladinosyl-3-oxoclarithromycin 11,12-carbamate

Suppliers and Price of 11-amino-N-(3-fluoro-4-morpholinophenyl)-2'-O-benzoyl-11-deoxy-3-O-descladinosyl-3-oxoclarithromycin 11,12-carbamate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 11-amino-N-(3-fluoro-4-morpholinophenyl)-2'-O-benzoyl-11-deoxy-3-O-descladinosyl-3-oxoclarithromycin 11,12-carbamate

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of 11-amino-N-(3-fluoro-4-morpholinophenyl)-2'-O-benzoyl-11-deoxy-3-O-descladinosyl-3-oxoclarithromycin 11,12-carbamate

There total 1 articles about 11-amino-N-(3-fluoro-4-morpholinophenyl)-2'-O-benzoyl-11-deoxy-3-O-descladinosyl-3-oxoclarithromycin 11,12-carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 17.0%

: 224323-51-7
3-fluoro-4-(morpholin-4-yl)-phenyl isocyanate

: C₃₇H₅₅NO₁₀

: 898833-60-8
11-amino-N-(3-fluoro-4-morpholinophenyl)-2'-O-benzoyl-11-deoxy-3-O-descladinosyl-3-oxoclarithromycin 11,12-carbamate

Guidance literature:: C₃₇H₅₅NO₁₀; With sodium hexamethyldisilazane; In tetrahydrofuran; at 20 ℃; for 0.166667h; Inert atmosphere;

3-fluoro-4-(morpholin-4-yl)-phenyl isocyanate; With copper(l) chloride; In tetrahydrofuran; at 50 ℃; for 42h;

Reference yield: 58.0%

: 898833-60-8
11-amino-N-(3-fluoro-4-morpholinophenyl)-2'-O-benzoyl-11-deoxy-3-O-descladinosyl-3-oxoclarithromycin 11,12-carbamate

: 898833-61-9
11-amino-N-(3-fluoro-4-morpholinophenyl)-11-deoxy-3-O-descladinosyl-3-oxoclarithromycin 11,12-carbamate

Guidance literature:: 11-amino-N-(3-fluoro-4-morpholinophenyl)-2'-O-benzoyl-11-deoxy-3-O-descladinosyl-3-oxoclarithromycin 11,12-carbamate; In methanol; at 30 - 40 ℃; for 96h;

With hydrogenchloride; water; In methanol; pH=~ 1;