N-trifluoroacetyl-4-benzylaminobenzonitrile

Base Information

• Chemical Name: N-trifluoroacetyl-4-benzylaminobenzonitrile
• CAS No.: 153982-19-5
• Molecular Formula: C₁₆H₁₁F₃N₂O
• Molecular Weight: 304.271
• Mol file: 153982-19-5.mol

Synonyms:N-trifluoroacetyl-4-benzylaminobenzonitrile

Chemical Property of N-trifluoroacetyl-4-benzylaminobenzonitrile

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of N-trifluoroacetyl-4-benzylaminobenzonitrile

There total 2 articles about N-trifluoroacetyl-4-benzylaminobenzonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-(benzylamino)benzonitrile (10282-32-3) + trifluoroacetic anhydride (407-25-0) → N-trifluoroacetyl-4-benzylaminobenzonitrile (153982-19-5)

Guidance literature:

With dmap; triethylamine; In dichloromethane; Ambient temperature;

DOI:10.1016/S0040-4039(00)76719-0

Reference yield:

→ 4-(benzylamino)benzonitrile (10282-32-3) + N-trifluoroacetyl-4-benzylaminobenzonitrile (153982-19-5)

Guidance literature:

Reference yield: 62.0%

N-trifluoroacetyl-4-benzylaminobenzonitrile (153982-19-5) → N-Benzyl-N-(4-cyano-phenyl)-2,2,2-trifluoro-thioacetamide

Guidance literature:

With Lawessons reagent; In toluene; at 100 ℃; for 12h;

DOI:10.1016/S0040-4039(00)76719-0

upstream raw materials:

4-(benzylamino)benzonitrile

trifluoroacetic anhydride

Downstream raw materials:

4-(benzylamino)benzonitrile