1,4-anhydro-2-deoxy-1-C-[4-[2-(methoxymethoxy)ethyl]phenyl]-D-erythro-pentitol 3,5-bis(4-methylbenzoate)

Base Information

• Chemical Name: 1,4-anhydro-2-deoxy-1-C-[4-[2-(methoxymethoxy)ethyl]phenyl]-D-erythro-pentitol 3,5-bis(4-methylbenzoate)
• CAS No.: 404567-08-4
• Molecular Formula: C₃₁H₃₄O₇
• Molecular Weight: 518.607

Synonyms:1,4-anhydro-2-deoxy-1-C-[4-[2-(methoxymethoxy)ethyl]phenyl]-D-erythro-pentitol 3,5-bis(4-methylbenzoate)

Chemical Property of 1,4-anhydro-2-deoxy-1-C-[4-[2-(methoxymethoxy)ethyl]phenyl]-D-erythro-pentitol 3,5-bis(4-methylbenzoate)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,4-anhydro-2-deoxy-1-C-[4-[2-(methoxymethoxy)ethyl]phenyl]-D-erythro-pentitol 3,5-bis(4-methylbenzoate)

There total 2 articles about 1,4-anhydro-2-deoxy-1-C-[4-[2-(methoxymethoxy)ethyl]phenyl]-D-erythro-pentitol 3,5-bis(4-methylbenzoate) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

2-deoxy-3,5-di-O-p-toluoyl-α-D-erythro-pentofuranosyl chloride (4330-21-6) + 1-bromo-4-[2-(methoxymethyloxy)ethyl]benzene (203664-53-3) → 1,4-anhydro-2-deoxy-1-C-[4-[2-(methoxymethoxy)ethyl]phenyl]-D-erythro-pentitol 3,5-bis(4-methylbenzoate) (404567-08-4)

Guidance literature:

1-bromo-4-[2-(methoxymethyloxy)ethyl]benzene; With iodine; magnesium; In tetrahydrofuran; at 50 ℃; for 2h;

2-deoxy-3,5-di-O-p-toluoyl-α-D-erythro-pentofuranosyl chloride; In tetrahydrofuran; at 20 ℃; for 12h; Further stages.;

DOI:10.1021/jo001676f

Reference yield:

4-bromophenethanol (4654-39-1) → 1,4-anhydro-2-deoxy-1-C-[4-[2-(methoxymethoxy)ethyl]phenyl]-D-erythro-pentitol 3,5-bis(4-methylbenzoate) (404567-08-4)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 96 percent / LiBr; p-TsOH*H₂O / 2 h / 20 °C

2.1: Mg; iodine / tetrahydrofuran / 2 h / 50 °C

2.2: 60 percent / tetrahydrofuran / 12 h / 20 °C

With iodine; toluene-4-sulfonic acid; magnesium; lithium bromide; In tetrahydrofuran;

DOI:10.1021/jo001676f

Reference yield: 90.0%

1,4-anhydro-2-deoxy-1-C-[4-[2-(methoxymethoxy)ethyl]phenyl]-D-erythro-pentitol 3,5-bis(4-methylbenzoate) (404567-08-4) → 1,4-anhydro-2-deoxy-1-C-[4-(2-hydroxyethyl)phenyl]-D-erythro-pentitol 3,5-bis(4-methylbenzoate) (404567-09-5)

Guidance literature:

With hydrogenchloride; In methanol; at 65 ℃;

DOI:10.1021/jo001676f

upstream raw materials:

2-deoxy-3,5-di-O-p-toluoyl-α-D-erythro-pentofuranosyl chloride

1-bromo-4-[2-(methoxymethyloxy)ethyl]benzene

4-bromophenethanol

Downstream raw materials:

1,4-anhydro-2-deoxy-1-C-[4-(2-hydroxyethyl)phenyl]-D-erythro-pentitol 3,5-bis(4-methylbenzoate)

1,4-anhydro-2-deoxy-1-C-[4-(2-azidoethyl)phenyl]-β-D-erythro-pentitol 3,5-bis(4-methylbenzoate)

1,4-anhydro-2-deoxy-1-C-[4-[2-[(methylsulfonyl)oxy]ethyl]phenyl]-D-erythro-pentitol 3,5-bis(4-methylbenzoate)

Pentanedioic acid {2-[4-((2R,4S,5R)-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-phenyl]-ethyl}-amide [4-((E)-styryl)-phenyl]-amide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 404567-08-4 1,4-anhydro-2-deoxy-1-C-[4-[2-(methoxymethoxy)ethyl]phenyl]-D-erythro-pentitol 3,5-bis(4-methylbenzoate)

Send

Send

Metric Ton KG G Pound L ML

Send

Send