7-Imino-1,7a-dimethyl-3-oxo-2-phenyl-2,3,7,7a-tetrahydro-1H-pyrazolo[4,3-c]pyridazine-6-carbonitrile

Base Information

• Chemical Name: 7-Imino-1,7a-dimethyl-3-oxo-2-phenyl-2,3,7,7a-tetrahydro-1H-pyrazolo[4,3-c]pyridazine-6-carbonitrile
• CAS No.: 82315-75-1
• Molecular Formula: C₁₄H₁₂N₆O
• Molecular Weight: 280.289
• Mol file: 82315-75-1.mol

Synonyms:7-Imino-1,7a-dimethyl-3-oxo-2-phenyl-2,3,7,7a-tetrahydro-1H-pyrazolo[4,3-c]pyridazine-6-carbonitrile

Chemical Property of 7-Imino-1,7a-dimethyl-3-oxo-2-phenyl-2,3,7,7a-tetrahydro-1H-pyrazolo[4,3-c]pyridazine-6-carbonitrile

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 7-Imino-1,7a-dimethyl-3-oxo-2-phenyl-2,3,7,7a-tetrahydro-1H-pyrazolo[4,3-c]pyridazine-6-carbonitrile

There total 3 articles about 7-Imino-1,7a-dimethyl-3-oxo-2-phenyl-2,3,7,7a-tetrahydro-1H-pyrazolo[4,3-c]pyridazine-6-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)carbono-hydrazonoyl dicyanide (81437-82-3) → 7-Imino-1,7a-dimethyl-3-oxo-2-phenyl-2,3,7,7a-tetrahydro-1H-pyrazolo[4,3-c]pyridazine-6-carbonitrile (82315-75-1)

Guidance literature:

With hydrogenchloride; In ethanol; for 2h; Heating;

Reference yield:

4-amino-1-methyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one (61341-50-2) → 7-Imino-1,7a-dimethyl-3-oxo-2-phenyl-2,3,7,7a-tetrahydro-1H-pyrazolo[4,3-c]pyridazine-6-carbonitrile (82315-75-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 70 percent / HCl, sodium nitrite, sodium acetate / ethanol / 2 h / Ambient temperature

2: 78 percent / HCl / ethanol / 2 h / Heating

With hydrogenchloride; sodium acetate; sodium nitrite; In ethanol;

Reference yield:

2-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-ylazo)-malononitrile → 7-Imino-1,7a-dimethyl-3-oxo-2-phenyl-2,3,7,7a-tetrahydro-1H-pyrazolo[4,3-c]pyridazine-6-carbonitrile (82315-75-1)

Guidance literature:

With hydrogenchloride; In ethanol; at 40 ℃; Kinetics; Rate constant; Thermodynamic data; other hydrazone, var. solvents, other temps.; ΔH(excit.), ΔS(excit.);

upstream raw materials:

(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)carbono-hydrazonoyl dicyanide

4-amino-1-methyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one