(E)-((2-iodohex-1-en-1-yl)sulfonyl)benzene

Base Information

• Chemical Name: (E)-((2-iodohex-1-en-1-yl)sulfonyl)benzene
• CAS No.: 1402133-13-4
• Molecular Formula: C₁₂H₁₅IO₂S
• Molecular Weight: 350.22
• Mol file: 1402133-13-4.mol

Synonyms:(E)-((2-iodohex-1-en-1-yl)sulfonyl)benzene

Chemical Property of (E)-((2-iodohex-1-en-1-yl)sulfonyl)benzene

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of (E)-((2-iodohex-1-en-1-yl)sulfonyl)benzene

There total 2 articles about (E)-((2-iodohex-1-en-1-yl)sulfonyl)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%

thiophenol (108-98-5) + hex-1-yne (693-02-7) → (E)-((2-iodohex-1-en-1-yl)sulfonyl)benzene (1402133-13-4)

Guidance literature:

thiophenol; With dihydrogen peroxide; iodine; In water; dimethyl sulfoxide; at 20 ℃; for 0.5h; Inert atmosphere; Green chemistry;

hex-1-yne; In water; dimethyl sulfoxide; at 100 ℃; stereoselective reaction; Inert atmosphere; Green chemistry;

DOI:10.1016/j.tet.2021.132310

Reference yield: 12.0%

hex-1-yne (693-02-7) + Benzenesulfinic acid (618-41-7) → (E)-((2-iodohex-1-en-1-yl)sulfonyl)benzene (1402133-13-4)

Guidance literature:

With iodine; In 1,2-dimethoxyethane; at 100 ℃; stereoselective reaction;

DOI:10.1039/c4ra13998d

Reference yield: 82.0%

(E)-((2-iodohex-1-en-1-yl)sulfonyl)benzene (1402133-13-4) + pent-4-ynyl-1-azide (199276-58-9) → (E)-(7-azido-2-butylhept-1-en-3-ynylsulfonyl)benzene (1402132-97-1)

Guidance literature:

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; diisopropylamine; In tetrahydrofuran; at 20 ℃; for 12h; Inert atmosphere;

DOI:10.1002/anie.201203678

upstream raw materials:

hex-1-yne

Benzenesulfinic acid

thiophenol

Downstream raw materials:

(E)-(7-azido-2-butylhept-1-en-3-ynylsulfonyl)benzene