4-carbamoylmethyl-5-(4-chlorophenyl)-1-(2-chlorophenyl)-1H-pyrazole-3-carboxylic acid 4-cyanobenzylamide

Base Information

Chemical Name:4-carbamoylmethyl-5-(4-chlorophenyl)-1-(2-chlorophenyl)-1H-pyrazole-3-carboxylic acid 4-cyanobenzylamide
CAS No.:1027617-10-2
Molecular Formula:C₂₆H₁₉Cl₂N₅O₂
Molecular Weight:504.375
Hs Code.:

Synonyms:4-carbamoylmethyl-5-(4-chlorophenyl)-1-(2-chlorophenyl)-1H-pyrazole-3-carboxylic acid 4-cyanobenzylamide

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Chemical Property of 4-carbamoylmethyl-5-(4-chlorophenyl)-1-(2-chlorophenyl)-1H-pyrazole-3-carboxylic acid 4-cyanobenzylamide

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Technology Process of 4-carbamoylmethyl-5-(4-chlorophenyl)-1-(2-chlorophenyl)-1H-pyrazole-3-carboxylic acid 4-cyanobenzylamide

There total 2 articles about 4-carbamoylmethyl-5-(4-chlorophenyl)-1-(2-chlorophenyl)-1H-pyrazole-3-carboxylic acid 4-cyanobenzylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 31.0%

: 1027617-58-8
4-carbamoylmethyl-5-(4-chlorophenyl)-1-(2-chlorophenyl)-1H-pyrazole-3-carboxylic acid

: 15996-76-6
4-cyanobenzylamine hydrochloride

: 1027617-10-2
4-carbamoylmethyl-5-(4-chlorophenyl)-1-(2-chlorophenyl)-1H-pyrazole-3-carboxylic acid 4-cyanobenzylamide

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃;

Reference yield:

: 1027617-58-8
4-carbamoylmethyl-5-(4-chlorophenyl)-1-(2-chlorophenyl)-1H-pyrazole-3-carboxylic acid

: 10406-25-4
4-aminobenzyl cyanide

: 1027617-10-2
4-carbamoylmethyl-5-(4-chlorophenyl)-1-(2-chlorophenyl)-1H-pyrazole-3-carboxylic acid 4-cyanobenzylamide

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2009.12.003