oxazol-5-yl(4-(tetrahydro-2H-pyran-2-yloxy)phenyl)methanone

Base Information

• Chemical Name: oxazol-5-yl(4-(tetrahydro-2H-pyran-2-yloxy)phenyl)methanone
• CAS No.: 929713-55-3
• Molecular Formula: C₁₅H₁₅NO₄
• Molecular Weight: 273.288
• Mol file: 929713-55-3.mol

Synonyms:oxazol-5-yl(4-(tetrahydro-2H-pyran-2-yloxy)phenyl)methanone

Chemical Property of oxazol-5-yl(4-(tetrahydro-2H-pyran-2-yloxy)phenyl)methanone

Chemical Property:

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Technology Process of oxazol-5-yl(4-(tetrahydro-2H-pyran-2-yloxy)phenyl)methanone

There total 1 articles about oxazol-5-yl(4-(tetrahydro-2H-pyran-2-yloxy)phenyl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

oxazol-5-yl(4-(tetrahydro-2H-pyran-2-yloxy)phenyl)methanol (929713-54-2) → oxazol-5-yl(4-(tetrahydro-2H-pyran-2-yloxy)phenyl)methanone (929713-55-3)

Guidance literature:

With Dess-Martin periodane; In dichloromethane; for 1h;

Reference yield: 67.0%

oxazol-5-yl(4-(tetrahydro-2H-pyran-2-yloxy)phenyl)methanone (929713-55-3) + trimethylsilanyl-acetic acid ethyl ester (4071-88-9) → ethyl 3-(oxazol-5-yl)-3-(4-(tetrahydro-2H-pyran-2-yloxy)phenyl)acrylate

Guidance literature:

oxazol-5-yl(4-(tetrahydro-2H-pyran-2-yloxy)phenyl)methanone; trimethylsilanyl-acetic acid ethyl ester; With lithium hexamethyldisilazane; In tetrahydrofuran; at -78 ℃; for 0.333333h; Inert atmosphere;

oxazol-5-yl(4-(tetrahydro-2H-pyran-2-yloxy)phenyl)methanone; In tetrahydrofuran; at -78 ℃; for 1.5h; Inert atmosphere;

DOI:10.1021/ml400501x

Reference yield:

oxazol-5-yl(4-(tetrahydro-2H-pyran-2-yloxy)phenyl)methanone (929713-55-3) + trimethylsilanyl-acetic acid ethyl ester (4071-88-9) → ethyl 3-(oxazol-5-yl)-3-(4-(tetrahydro-2H-pyran-2-yloxy)phenyl)acrylate

Guidance literature:

With lithium hexamethyldisilazane; In tetrahydrofuran; at -78 ℃; for 1.83333h;

upstream raw materials:

oxazol-5-yl(4-(tetrahydro-2H-pyran-2-yloxy)phenyl)methanol