C₃₄H₃₃IO₇

Base Information

• Chemical Name: C₃₄H₃₃IO₇
• CAS No.: 1193357-61-7
• Molecular Formula: C₃₄H₃₃IO₇
• Molecular Weight: 680.536
• Mol file: 1193357-61-7.mol

Synonyms:C₃₄H₃₃IO₇

Chemical Property of C₃₄H₃₃IO₇

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₄H₃₃IO₇

There total 12 articles about C₃₄H₃₃IO₇ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

3,5-bis-benzyloxy-2-iodo-phenol + C14H18O5 (1239861-07-4) → C34H33IO7 (1193357-61-7)

Guidance literature:

With tributylphosphine; diamide; In toluene; at 0 - 20 ℃; for 2.5h; stereospecific reaction; Inert atmosphere;

DOI:10.1246/cl.2009.934

Reference yield:

di-tert-butyl dicarbonate (24424-99-5) → C34H33IO7 (1193357-61-7)

Guidance literature:

Multi-step reaction with 3 steps

1.1: dmap / dichloromethane / 1 h / 20 °C / Inert atmosphere

2.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 1 h / 0 °C / Inert atmosphere

2.2: Inert atmosphere

3.1: tributylphosphine; diamide / toluene / 2.5 h / 0 - 20 °C / Inert atmosphere

With dmap; tributylphosphine; diamide; tetrabutyl ammonium fluoride; In tetrahydrofuran; dichloromethane; toluene; 3.1: |Mitsunobu Displacement;

DOI:10.1246/cl.2009.934

Reference yield:

4-hydroxy-benzaldehyde (123-08-0,65581-83-1) → C34H33IO7 (1193357-61-7)

Guidance literature:

Multi-step reaction with 11 steps

1.1: potassium carbonate / acetone / 2 h / Reflux; Inert atmosphere

2.1: sodium hydride / tetrahydrofuran; mineral oil / 1 h / 0 °C / Inert atmosphere

2.2: 16 h / 0 °C / Inert atmosphere

3.1: diisobutylaluminium hydride / tetrahydrofuran / 2 h / -78 °C / Inert atmosphere

3.2: 0 - 20 °C / Inert atmosphere

4.1: methanesulfonamide; AD-mix β / water; tert-butyl alcohol / 3.8 h / 0 °C / Inert atmosphere

5.1: pyridine / dichloromethane / 29 h / 0 - 20 °C / Inert atmosphere

6.1: potassium carbonate / methanol / 3 h / 0 °C / Inert atmosphere

7.1: 1H-imidazole / N,N-dimethyl-formamide / 2 h / 0 - 20 °C / Inert atmosphere

8.1: 10 wt% Pd(OH)2 on carbon; hydrogen / ethyl acetate / 6.5 h / 20 °C

9.1: dmap / dichloromethane / 1 h / 20 °C / Inert atmosphere

10.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 1 h / 0 °C / Inert atmosphere

10.2: Inert atmosphere

11.1: tributylphosphine; diamide / toluene / 2.5 h / 0 - 20 °C / Inert atmosphere

With pyridine; 1H-imidazole; dmap; tributylphosphine; methanesulfonamide; diamide; AD-mix β; 10 wt% Pd(OH)2 on carbon; tetrabutyl ammonium fluoride; hydrogen; sodium hydride; diisobutylaluminium hydride; potassium carbonate; In tetrahydrofuran; methanol; dichloromethane; water; ethyl acetate; N,N-dimethyl-formamide; acetone; toluene; mineral oil; tert-butyl alcohol; 11.1: |Mitsunobu Displacement;

DOI:10.1246/cl.2009.934

upstream raw materials:

C₁₄H₁₈O₅

4-hydroxy-benzaldehyde

p-benzyloxybenzaldehyde

Z-methyl 3-(4-benzyloxy)phenylacrylate

Downstream raw materials:

C₃₄H₃₄BrIO₇

C₄₀H₄₈BrIO₇Si

C₄₀H₄₈O₇Si

C₃₅H₄₀O₅Si