(2S,4S)-3-acetyl-5,5-dimethyl-2-(2-methoxyphenyl)-4-thiazolidinecarboxylic acid

Base Information

Chemical Name:(2S,4S)-3-acetyl-5,5-dimethyl-2-(2-methoxyphenyl)-4-thiazolidinecarboxylic acid
CAS No.:125813-83-4
Molecular Formula:C₁₅H₁₉NO₄S
Molecular Weight:309.386
Hs Code.:

Synonyms:(2S,4S)-3-acetyl-5,5-dimethyl-2-(2-methoxyphenyl)-4-thiazolidinecarboxylic acid

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Chemical Property of (2S,4S)-3-acetyl-5,5-dimethyl-2-(2-methoxyphenyl)-4-thiazolidinecarboxylic acid

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Technology Process of (2S,4S)-3-acetyl-5,5-dimethyl-2-(2-methoxyphenyl)-4-thiazolidinecarboxylic acid

There total 3 articles about (2S,4S)-3-acetyl-5,5-dimethyl-2-(2-methoxyphenyl)-4-thiazolidinecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 125813-71-0
(4S)-5,5-dimethyl-2-(2-methoxyphenyl)-4-thiazolidinecarboxylic acid

: 108-24-7
acetic anhydride

: 125813-83-4
(2S,4S)-3-acetyl-5,5-dimethyl-2-(2-methoxyphenyl)-4-thiazolidinecarboxylic acid

Guidance literature:: In water; at 80 ℃; for 10h;
DOI:10.1021/jm00169a011

Reference yield:

: 52-67-5
3,3-dimethyl-D-cysteine

: 125813-83-4
(2S,4S)-3-acetyl-5,5-dimethyl-2-(2-methoxyphenyl)-4-thiazolidinecarboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 63.7 g / ethanol; H₂O / 1 h / Ambient temperature

2: 71 percent / H₂O / 10 h / 80 °C

In ethanol; water;
DOI:10.1021/jm00169a011

Reference yield:

: 135-02-4
ortho-anisaldehyde

: 125813-83-4
(2S,4S)-3-acetyl-5,5-dimethyl-2-(2-methoxyphenyl)-4-thiazolidinecarboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 63.7 g / ethanol; H₂O / 1 h / Ambient temperature

2: 71 percent / H₂O / 10 h / 80 °C

In ethanol; water;
DOI:10.1021/jm00169a011