4'-acetylamino-6-aminobiphenyl-3-carboxylic acid (4-dibenzylaminophenyl)amide

Base Information

• Chemical Name: 4'-acetylamino-6-aminobiphenyl-3-carboxylic acid (4-dibenzylaminophenyl)amide
• CAS No.: 1032373-91-3
• Molecular Formula: C₃₅H₃₂N₄O₂
• Molecular Weight: 540.665
• Mol file: 1032373-91-3.mol

Synonyms:4'-acetylamino-6-aminobiphenyl-3-carboxylic acid (4-dibenzylaminophenyl)amide

Chemical Property of 4'-acetylamino-6-aminobiphenyl-3-carboxylic acid (4-dibenzylaminophenyl)amide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4'-acetylamino-6-aminobiphenyl-3-carboxylic acid (4-dibenzylaminophenyl)amide

There total 1 articles about 4'-acetylamino-6-aminobiphenyl-3-carboxylic acid (4-dibenzylaminophenyl)amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

4-amino-3-bromo-N-(4-dibenzylaminophenyl)benzamide (1032373-87-7) + (4-acetylaminophenyl)boronic acid (101251-09-6) → 4'-acetylamino-6-aminobiphenyl-3-carboxylic acid (4-dibenzylaminophenyl)amide (1032373-91-3)

Guidance literature:

With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; potassium carbonate; In N,N-dimethyl-formamide; at 100 ℃; for 20h; Inert atmosphere;

DOI:10.1016/j.bmc.2008.09.058

Reference yield: 41.0%

4'-acetylamino-6-aminobiphenyl-3-carboxylic acid (4-dibenzylaminophenyl)amide (1032373-91-3) + N-(t-butoxycarbonyl)glycinal (89711-08-0) → 4'-acetylamino-6-(2-aminoethylamino)biphenyl-3-carboxylic acid (4-dibenzylaminophenyl)amide (1032374-07-4)

Guidance literature:

4'-acetylamino-6-aminobiphenyl-3-carboxylic acid (4-dibenzylaminophenyl)amide; N-(t-butoxycarbonyl)glycinal; In methanol; acetic acid; 4A molecular sieves;

With sodium cyanoborohydride; In methanol; acetic acid;

With trifluoroacetic acid; In methanol; acetic acid;

Reference yield:

4'-acetylamino-6-aminobiphenyl-3-carboxylic acid (4-dibenzylaminophenyl)amide (1032373-91-3) + N-(t-butoxycarbonyl)glycinal (89711-08-0) → C42H45N5O4 (1032373-99-1)

Guidance literature:

4'-acetylamino-6-aminobiphenyl-3-carboxylic acid (4-dibenzylaminophenyl)amide; N-(t-butoxycarbonyl)glycinal; With acetic acid; In methanol; at 20 ℃; for 1h; Molecular sieve; Inert atmosphere;

With sodium cyanoborohydride; In methanol; at 20 ℃; Molecular sieve; Inert atmosphere;

DOI:10.1016/j.bmc.2008.09.058

upstream raw materials:

4-amino-3-bromo-N-(4-dibenzylaminophenyl)benzamide

(4-acetylaminophenyl)boronic acid

Downstream raw materials:

4'-acetylamino-6-(2-aminoethylamino)biphenyl-3-carboxylic acid (4-dibenzylaminophenyl)amide

C₄₂H₄₅N₅O₄