1-(2-Aminothiophen-3-yl)ethanone

Base Information

• Chemical Name: 1-(2-Aminothiophen-3-yl)ethanone
• CAS No.: 892127-08-1
• Molecular Formula: C₆H₇NOS
• Molecular Weight: 141.194
• Hs Code.: 2934999090
• European Community (EC) Number: 838-434-5
• DSSTox Substance ID: DTXSID701008721
• Wikidata: Q83005267
• Mol file: 892127-08-1.mol

Synonyms:892127-08-1;1-(2-aminothiophen-3-yl)ethanone;1-(2-AMINO-THIOPHEN-3-YL)-ETHANONE;1-(2-AMINOTHIOPHEN-3-YL)ETHAN-1-ONE;1-(2-AMINO-3-THIENYL)ETHANONE;Ethanone, 1-(2-amino-3-thienyl)- (9CI);MFCD16657014;ETHANONE,1-(2-AMINO-3-THIENYL)-;3-acetyl-2-aminothiophene;SCHEMBL3044354;DTXSID701008721;AKOS005137936;AB71423;AS-76129;SY198401;DB-078326;CS-0155129;D95065;EN300-218982

Chemical Property of 1-(2-Aminothiophen-3-yl)ethanone

Chemical Property:

• Vapor Pressure: 0.00948mmHg at 25°C
• Refractive Index: 1.606
• Boiling Point: 264.8°C at 760 mmHg
• Flash Point: 114°C
• PSA: 71.33000
• Density: 1.252g/cm³
• LogP: 2.11410
• Storage Temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
• XLogP3: 1.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 141.02483502
• Heavy Atom Count: 9
• Complexity: 126

Purity/Quality:

98%min ^*data from raw suppliers

1-(2-Amino-thiophen-3-yl)-ethanone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)C1=C(SC=C1)N

Technology Process of 1-(2-Aminothiophen-3-yl)ethanone

There total 1 articles about 1-(2-Aminothiophen-3-yl)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

1,4-dithiane-2,5-diol (40018-26-6) + Cyanoaceton (2469-99-0) → 1-(2-amino-3-thienyl)ethanone (892127-08-1)

Guidance literature:

With triethylamine; In N,N-dimethyl-formamide; at 60 ℃; for 3h;

DOI:10.3390/11050371

upstream raw materials:

1,4-dithiane-2,5-diol

Cyanoaceton