Technology Process of C12(13)CH14N2O2
There total 8 articles about C12(13)CH14N2O2 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
ethyl 1-benzyl-2,3-dihydro-2-thioxo-5-imidazole-carboxylate;
With
nitric acid; sodium nitrite;
In
water;
for 0.5h;
With
sodium carbonate;
In
water;
Heating;
DOI:10.3390/molecules19011023
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: sodium thioethylate / N,N-dimethyl-formamide / Reflux
2.1: sodium nitrite; nitric acid / water / 0.5 h
2.2: Heating
With
nitric acid; sodium nitrite; sodium thioethylate;
In
water; N,N-dimethyl-formamide;
DOI:10.3390/molecules19011023
- Guidance literature:
-
Multi-step reaction with 8 steps
1.1: bis(triphenylphosphine)iminium chloride / 1,2-dichloro-benzene / 3 h / 180 °C
1.2: -30 - 0 °C / pH 8.5
2.1: hydrogenchloride / acetone / 40 °C
3.1: potassium carbonate / acetonitrile / 14 h / 40 °C
4.1: tetrahydrofuran / 0.17 h / 20 °C
5.1: boron trifluoride diethyl etherate / benzene / 2 h / 20 °C / Inert atmosphere
6.1: sulfuric acid / 24 h / 0 °C / Reflux
7.1: sodium thioethylate / N,N-dimethyl-formamide / Reflux
8.1: sodium nitrite; nitric acid / water / 0.5 h
8.2: Heating
With
hydrogenchloride; sulfuric acid; boron trifluoride diethyl etherate; nitric acid; bis(triphenylphosphine)iminium chloride; potassium carbonate; sodium nitrite; sodium thioethylate;
In
tetrahydrofuran; water; N,N-dimethyl-formamide; 1,2-dichloro-benzene; acetone; acetonitrile; benzene;
DOI:10.3390/molecules19011023
