1-(4-AMINO-PHENYL)-PIPERIDINE-3-CARBOXYLIC ACID ETHYL ESTER

Base Information

• Chemical Name: 1-(4-AMINO-PHENYL)-PIPERIDINE-3-CARBOXYLIC ACID ETHYL ESTER
• CAS No.: 889947-74-4
• Molecular Formula: C14H20 N2 O2
• Molecular Weight: 248.32
• Mol file: 889947-74-4.mol

Synonyms:1-(4-AMINO-PHENYL)-PIPERIDINE-3-CARBOXYLIC ACID ETHYL ESTER

Chemical Property of 1-(4-AMINO-PHENYL)-PIPERIDINE-3-CARBOXYLIC ACID ETHYL ESTER

Chemical Property:

• Boiling Point: 410.7±40.0 °C(Predicted)
• PKA: 7.79±0.10(Predicted)
• PSA: 55.56000
• Density: 1.138±0.06 g/cm3(Predicted)
• LogP: 2.69450
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

1-(4-amino-phenyl)-piperidine-3-carboxylicacidethylester 95 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-(4-AMINO-PHENYL)-PIPERIDINE-3-CARBOXYLIC ACID ETHYL ESTER

There total 3 articles about 1-(4-AMINO-PHENYL)-PIPERIDINE-3-CARBOXYLIC ACID ETHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl 1-(4-nitrophenyl)piperidine-3-carboxylate (911105-84-5) → ethyl 1-(4-aminophenyl)piperidine-3-carboxylate (889947-74-4)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In ethanol; at 20 ℃; under 760.051 Torr;

DOI:10.1039/c3md00250k

Reference yield:

Ethyl nipecotate (71962-74-8) → ethyl 1-(4-aminophenyl)piperidine-3-carboxylate (889947-74-4)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / dimethyl sulfoxide / 15 h / 55 °C

2: palladium 10% on activated carbon; hydrogen / ethanol / 20 °C / 760.05 Torr

With palladium 10% on activated carbon; hydrogen; potassium carbonate; In ethanol; dimethyl sulfoxide;

DOI:10.1039/c3md00250k

Reference yield:

4-Fluoronitrobenzene (350-46-9,178603-76-4) → ethyl 1-(4-aminophenyl)piperidine-3-carboxylate (889947-74-4)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / dimethyl sulfoxide / 15 h / 55 °C

2: palladium 10% on activated carbon; hydrogen / ethanol / 20 °C / 760.05 Torr

With palladium 10% on activated carbon; hydrogen; potassium carbonate; In ethanol; dimethyl sulfoxide;

DOI:10.1039/c3md00250k

upstream raw materials:

ethyl 1-(4-nitrophenyl)piperidine-3-carboxylate

Ethyl nipecotate

4-Fluoronitrobenzene

Downstream raw materials:

ethyl 1-(4-(((S)-3-(1,3-dioxoisoindolin-2-yl)-2-hydroxypropyl)amino)phenyl)piperidine-3-carboxylate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 889947-74-4 1-(4-AMINO-PHENYL)-PIPERIDINE-3-CARBOXYLIC ACID ETHYL ESTER

Send

Send

Metric Ton KG G Pound L ML

Send

Send