(S)-2-[(R)-2-(4-fluoro-phenyl)-piperidin-1-yl]-2-phenyl-ethanol hydrochloride

Base Information

Chemical Name:(S)-2-[(R)-2-(4-fluoro-phenyl)-piperidin-1-yl]-2-phenyl-ethanol hydrochloride
CAS No.:1187468-20-7
Molecular Formula:C₁₉H₂₂FNO*ClH
Molecular Weight:335.849
Hs Code.:

Synonyms:(S)-2-[(R)-2-(4-fluoro-phenyl)-piperidin-1-yl]-2-phenyl-ethanol hydrochloride

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (S)-2-[(R)-2-(4-fluoro-phenyl)-piperidin-1-yl]-2-phenyl-ethanol hydrochloride

Chemical Property:

Purity/Quality:

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Technology Process of (S)-2-[(R)-2-(4-fluoro-phenyl)-piperidin-1-yl]-2-phenyl-ethanol hydrochloride

There total 4 articles about (S)-2-[(R)-2-(4-fluoro-phenyl)-piperidin-1-yl]-2-phenyl-ethanol hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1187483-59-5
(S)-2-[(R)-2-(4-fluoro-phenyl)-piperidin-1-yl]-2-phenyl-ethanol

: 1187468-20-7
(S)-2-[(R)-2-(4-fluoro-phenyl)-piperidin-1-yl]-2-phenyl-ethanol hydrochloride

Guidance literature:: With hydrogenchloride; In diethyl ether; dichloromethane;

Reference yield:

: 1187468-19-4
(3S,8aS)-8a-(4-fluoro-phenyl)-3-phenyl-hexahydro-oxazolo[3,2-a]pyridin-5-one

: 1187468-20-7
(S)-2-[(R)-2-(4-fluoro-phenyl)-piperidin-1-yl]-2-phenyl-ethanol hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: aluminum (III) chloride; lithium aluminium tetrahydride / tetrahydrofuran / -78 - 20 °C

2: hydrogenchloride / diethyl ether; dichloromethane

With hydrogenchloride; aluminum (III) chloride; lithium aluminium tetrahydride; In tetrahydrofuran; diethyl ether; dichloromethane;

Reference yield:

: 20989-17-7
(2S)-2-phenylglycinol

: 1187468-20-7
(S)-2-[(R)-2-(4-fluoro-phenyl)-piperidin-1-yl]-2-phenyl-ethanol hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: toluene / 20 h / 140 °C / Molecular sieve

2: aluminum (III) chloride; lithium aluminium tetrahydride / tetrahydrofuran / -78 - 20 °C

3: hydrogenchloride / diethyl ether; dichloromethane

With hydrogenchloride; aluminum (III) chloride; lithium aluminium tetrahydride; In tetrahydrofuran; diethyl ether; dichloromethane; toluene;