6-(2-Trifluoromethylphenyl)-picolinic acid

Base Information

• Chemical Name: 6-(2-Trifluoromethylphenyl)-picolinic acid
• CAS No.: 887983-43-9
• Molecular Formula: C₁₃H₈F₃NO₂
• Molecular Weight: 267.207
• Mol file: 887983-43-9.mol

Synonyms:6-(2-Trifluoromethylphenyl)-picolinic acid

Chemical Property of 6-(2-Trifluoromethylphenyl)-picolinic acid

Chemical Property:

• PSA: 50.19000
• LogP: 3.46560
• Storage Temp.: 2-8°C

Purity/Quality:

98%min ^*data from raw suppliers

6-(2-Trifluoromethylphenyl)-2-pyridinecarboxylicacid 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-(2-Trifluoromethylphenyl)-picolinic acid

There total 1 articles about 6-(2-Trifluoromethylphenyl)-picolinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

6-bromo-pyridine-2-carboxylic acid (21190-87-4) + 2-(trifluoromethyl)phenylboronic acid (1423-27-4) → 6-(2-trifluoromethylphenyl)pyridine-2-carboxylic acid (887983-43-9)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In 1,2-dimethoxyethane; for 12h; Inert atmosphere; Schlenk technique; Reflux;

DOI:10.1246/bcsj.20190134

upstream raw materials:

6-bromo-pyridine-2-carboxylic acid

2-(trifluoromethyl)phenylboronic acid