N-tert-butoxycarbonyl-L-phenylalanine-L-glutamate dibenzykester

Base Information

• Chemical Name: N-tert-butoxycarbonyl-L-phenylalanine-L-glutamate dibenzykester
• CAS No.: 176448-92-3
• Molecular Formula: C₃₃H₃₈N₂O₇
• Molecular Weight: 574.674
• Mol file: 176448-92-3.mol

Synonyms:N-tert-butoxycarbonyl-L-phenylalanine-L-glutamate dibenzykester

Chemical Property of N-tert-butoxycarbonyl-L-phenylalanine-L-glutamate dibenzykester

Chemical Property:

Purity/Quality:

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Technology Process of N-tert-butoxycarbonyl-L-phenylalanine-L-glutamate dibenzykester

There total 1 articles about N-tert-butoxycarbonyl-L-phenylalanine-L-glutamate dibenzykester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

N-tert-butoxycarbonyl-L-phenylalanine (13734-34-4) + L-glutamic acid dibenzyl ester 4-toluenesulfonate (2791-84-6,227205-81-4) → N-tert-butoxycarbonyl-L-phenylalanine-L-glutamate dibenzykester (176448-92-3)

Guidance literature:

With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In dichloromethane; N,N-dimethyl-formamide; at 20 ℃;

DOI:10.1016/j.ejmech.2008.01.032

Reference yield: 89.0%

N-tert-butoxycarbonyl-L-phenylalanine-L-glutamate dibenzykester (176448-92-3) → L-phenylalanine-L-glutamate dibenzylester (195072-86-7)

Guidance literature:

With chlorotriisopropylsilane; trifluoroacetic acid; In dichloromethane; at 20 ℃; for 12h; Cooling with ice;

DOI:10.1016/j.ejmech.2008.01.032

upstream raw materials:

N-tert-butoxycarbonyl-L-phenylalanine

L-glutamic acid dibenzyl ester 4-toluenesulfonate

Downstream raw materials:

L-phenylalanine-L-glutamate dibenzylester